The American bison, also called the American buffalo or simply buffalo, is a species of bison native to North America. It is one of two extant species of bison, alongside the European bison. Its historical range circa 9000 BC is described as the great bison belt, a tract of rich grassland from Alaska to the Gulf of Mexico, east to the Atlantic Seaboard, as far north as New York, south to Georgia, and according to some sources, further south to northern Florida, with sightings in North Carolina near Buffalo Ford on the Catawba River as late as 1750.

Plains Indians or Indigenous peoples of the Great Plains and Canadian Prairies are the Native American tribes and First Nation band governments who have historically lived on the Interior Plains of North America. While hunting-farming cultures have lived on the Great Plains for centuries prior to European contact, the region is known for the horse cultures that flourished from the 17th century through the late 19th century. Their historic nomadism and armed resistance to domination by the government and military forces of Canada and the United States have made the Plains Indian culture groups an archetype in literature and art for Native Americans everywhere.