1.
Seleucid Empire
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Seleucus received Babylonia and, from there, expanded his dominions to include much of Alexanders near eastern territories. At the height of its power, it included central Anatolia, Persia, the Levant, Mesopotamia, and what is now Kuwait, Afghanistan, and parts of Pakistan and Turkmenistan. The Seleucid Empire was a center of Hellenistic culture that maintained the preeminence of Greek customs where a Greek political elite dominated. The Greek population of the cities who formed the dominant elite were reinforced by immigration from Greece, Seleucid expansion into Anatolia and Greece was abruptly halted after decisive defeats at the hands of the Roman army. Their attempts to defeat their old enemy Ptolemaic Egypt were frustrated by Roman demands, contemporary sources, such as a loyalist degree from Ilium, in Greek language define the Seleucid state both as an empire and as a kingdom. Similarly, Seleucid rulers were described as kings in Babylonia and he refers to either Alexander Balas or Alexander II Zabinas as a ruler. Alexander, who conquered the Persian Empire under its last Achaemenid dynast, Darius III, died young in 323 BC. Alexanders generals jostled for supremacy over parts of his empire, Ptolemy, a former general and the satrap of Egypt, was the first to challenge the new system, this led to the demise of Perdiccas. Ptolemys revolt led to a new subdivision of the empire with the Partition of Triparadisus in 320 BC, Seleucus, who had been Commander-in-Chief of the Companion cavalry and appointed first or court chiliarch received Babylonia and, from that point, continued to expand his dominions ruthlessly. Seleucus established himself in Babylon in 312 BC, the used as the foundation date of the Seleucid Empire. The whole region from Phrygia to the Indus was subject to Seleucus, but Seleucus Nicator gave them to Sandrocottus in consequence of a marriage contract, and received in return five hundred elephants. Following his and Lysimachus victory over Antigonus Monophthalmus at the decisive Battle of Ipsus in 301 BC, Seleucus took control over eastern Anatolia, in the latter area, he founded a new capital at Antioch on the Orontes, a city he named after his father. An alternative capital was established at Seleucia on the Tigris, north of Babylon, Seleucuss empire reached its greatest extent following his defeat of his erstwhile ally, Lysimachus, at Corupedion in 281 BC, after which Seleucus expanded his control to encompass western Anatolia. He hoped further to take control of Lysimachuss lands in Europe – primarily Thrace and even Macedonia itself, nevertheless, even before Seleucus death, it was difficult to assert control over the vast eastern domains of the Seleucids. Seleucus invaded the Punjab region of India in 305 BC, confronting Chandragupta Maurya and it is said that Chandragupta fielded an army of 600,000 men and 9,000 war elephants. Archaeologically, concrete indications of Mauryan rule, such as the inscriptions of the Edicts of Ashoka, are known as far as Kandahar in southern Afghanistan and it is generally thought that Chandragupta married Seleucuss daughter, or a Macedonian princess, a gift from Seleucus to formalize an alliance. In a return gesture, Chandragupta sent 500 war elephants, an asset which would play a decisive role at the Battle of Ipsus in 301 BC. In addition to this treaty, Seleucus dispatched an ambassador, Megasthenes, to Chandragupta, Megasthenes wrote detailed descriptions of India and Chandraguptas reign, which have been partly preserved to us through Diodorus Siculus
2.
Syria
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Syrias capital and largest city is Damascus. Religious groups include Sunnis, Christians, Alawites, Druze, Mandeans, Shiites, Salafis, Sunni Arabs make up the largest religious group in Syria. Its capital Damascus and largest city Aleppo are among the oldest continuously inhabited cities in the world, in the Islamic era, Damascus was the seat of the Umayyad Caliphate and a provincial capital of the Mamluk Sultanate in Egypt. The post-independence period was tumultuous, and a number of military coups. In 1958, Syria entered a union with Egypt called the United Arab Republic. Syria was under Emergency Law from 1963 to 2011, effectively suspending most constitutional protections for citizens, Bashar al-Assad has been president since 2000 and was preceded by his father Hafez al-Assad, who was in office from 1970 to 2000. Mainstream modern academic opinion strongly favours the argument that the Greek word is related to the cognate Ἀσσυρία, Assyria, in the past, others believed that it was derived from Siryon, the name that the Sidonians gave to Mount Hermon. However, the discovery of the inscription in 2000 seems to support the theory that the term Syria derives from Assyria. The area designated by the word has changed over time, since approximately 10,000 BC, Syria was one of centers of Neolithic culture where agriculture and cattle breeding appeared for the first time in the world. The following Neolithic period is represented by houses of Mureybet culture. At the time of the pre-pottery Neolithic, people used vessels made of stone, gyps, finds of obsidian tools from Anatolia are evidences of early trade relations. Cities of Hamoukar and Emar played an important role during the late Neolithic, archaeologists have demonstrated that civilization in Syria was one of the most ancient on earth, perhaps preceded by only those of Mesopotamia. The earliest recorded indigenous civilisation in the region was the Kingdom of Ebla near present-day Idlib, gifts from Pharaohs, found during excavations, confirm Eblas contact with Egypt. One of the earliest written texts from Syria is an agreement between Vizier Ibrium of Ebla and an ambiguous kingdom called Abarsal c.2300 BC. The Northwest Semitic language of the Amorites is the earliest attested of the Canaanite languages, Mari reemerged during this period, and saw renewed prosperity until conquered by Hammurabi of Babylon. Ugarit also arose during this time, circa 1800 BC, close to modern Latakia, Ugaritic was a Semitic language loosely related to the Canaanite languages, and developed the Ugaritic alphabet. The Ugarites kingdom survived until its destruction at the hands of the marauding Indo-European Sea Peoples in the 12th century BC, Yamhad was described in the tablets of Mari as the mightiest state in the near east and as having more vassals than Hammurabi of Babylon. Yamhad imposed its authority over Alalakh, Qatna, the Hurrians states, the army of Yamhad campaigned as far away as Dēr on the border of Elam
3.
Cleopatra Thea
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Cleopatra Thea surnamed Eueteria was the ruler of the Hellenistic Seleucid Empire. She ruled Syria from 125 BC after the death of Demetrius II Nicator and she eventually ruled in co-regency with her son Antiochus VIII Grypus until 121 or 120 BC. Cleopatra Thea grew up in Egypt as the daughter of Ptolemy VI and she was probably born ca.164 BC. She may have engaged to her uncle Ptolemy VIII king of Cyrene in 154. In 150 BC she married Alexander Balas in a ceremony at Ptolemais Akko. The marriage produced a son named Antiochus VI Dionysus, in 145 BC her father invaded Syria, defeated Alexander Balas in battle and remarried her to Demetrius II, only to die a few days later. Demetrius set himself up as co-ruler with the young boy Antiochus VI, in 139 BC Demetrius II was captured fighting against the Parthians and was held prisoner by them until 129 BC. After Demetrius was captured, his brother, Antiochus VII Sidetes. Cleopatra Thea bore him at least one son, Antiochus IX Cyzicenus, the names of any other children are uncertain. In 129 BC, the Parthians released Demetrius II, as a political manoeuvre against Sidetes, to claim his throne and that same year Sidetes was killed fighting the Parthians. Cleopatra had taken the precaution of sending Antiochus IX to Cyzicus in Asia Minor, Demetrius returned home and regained his throne, taking Cleopatra Thea as his wife by his side. In 132/131 BC Cleopatra Theas mother, Cleopatra II of Egypt rebelled against her brother Ptolemy VIII Euergetes II Tryphon, in 127 BC Cleopatra II fled to her son-in-law Demetrius court in Syria. Demetrius elder son, Seleucus, became king with the name Seleucus V in 125 BC, however, his mother, from 125 BC to 121 BC, Cleopatra ruled Syria and to legitimize her reign, she shared the throne with her son, Antiochus VIII Grypus. Antiochus VIII was married to Tryphaena, the daughter of Ptolemy VIII, Grypus became less controllable as he grew up and in 121 BC Cleopatra Thea decided to eliminate him. As he returned from a hunt one day, she offered him a cup of wine, since this was not common behavior for her, Grypus was suspicious and forced her to drink the wine, which killed her. Grypus re-organised the state and for the eight years he provided stability. This period would end ca.114 BC, when Cleopatra Theas other son, Antiochus IX Cyzicenus, returned to Syria to claim the throne, Cleopatra Thea was a daughter of Ptolemy VI of Egypt and Cleopatra II. She had two brothers named Ptolemy Eupator and Ptolemy respectively and her sister Cleopatra III was Queen of Egypt and married to Ptolemy VIII, an uncle
4.
Antiochus IX Cyzicenus
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Antiochus IX Eusebes Cyzicenus, ruler of the Greek Seleucid kingdom, was the son of Antiochus VII Sidetes and Cleopatra Thea. After the death of his mother Cleopatra Thea ca.118 BCE, Antiochus IX Cyzicenus challenged his half-brother, Antiochus VIII Grypus, for power of Syria. Antiochus IX Cyzicenus was first married to Cleopatra IV, who was killed in 112 BC by her sister and rival Syrian Queen Tryphaena. After the death of Grypus and capturing the capital, Antiochus IX Cyzicenus married Cleopatra Selene I and he was killed in battle by the son of Grypus, Seleucus VI Epiphanes in 96 BC. The epithets he took much of his story, Eusebes. After that, he ruled Antioch and its surroundings, fighting endlessly against the four brothers of Seleucus VI, the Nabataeans, list of Syrian monarchs Timeline of Syrian history Antiochus IX Cyzicenus entry in historical sourcebook by Mahlon H. Smith
5.
Coronation
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The ceremony can also be conducted for the monarchs consort, either simultaneously with the monarch or as a separate event. A ceremony without the placement of a crown on the head is known as an enthronement. Coronations are still observed in the United Kingdom, Tonga, in addition to investing the monarch with symbols of state, Western-style coronations have often traditionally involve anointing with holy oil, or chrism as it is often called. Wherever a ruler is anointed in this way, as in Great Britain and Tonga, some other lands use bathing or cleansing rites, the drinking of a sacred beverage, or other religious practices to achieve a comparable effect. Such acts symbolise the granting of divine favour to the monarch within the relevant spiritual-religious paradigm of the country, in the past, concepts of royalty, coronation and deity were often inexorably linked. Rome promulgated the practice of worship, in Medieval Europe. Coronations were once a direct expression of these alleged connections. Thus, coronations have often been discarded altogether or altered to reflect the nature of the states in which they are held. However, some monarchies still choose to retain an overtly religious dimension to their accession rituals, others have adopted simpler enthronement or inauguration ceremonies, or even no ceremony at all. In non-Christian states, coronation rites evolved from a variety of sources, buddhism, for instance, influenced the coronation rituals of Thailand, Cambodia and Bhutan, while Hindu elements played a significant role in Nepalese rites. The ceremonies used in modern Egypt, Malaysia, Brunei and Iran were shaped by Islam, Coronations, in one form or another, have existed since ancient times. Egyptian records show coronation scenes, such as that of Seti I in 1290 BC, judeo-Christian scriptures testify to particular rites associated with the conferring of kingship, the most detailed accounts of which are found in II Kings 11,12 and II Chronicles 23,11. Following the assumption of the diadem by Constantine, Roman and Byzantine emperors continued to wear it as the symbol of their authority. Although no specific coronation ceremony was observed at first, one gradually evolved over the following century, the emperor Julian was hoisted upon a shield and crowned with a gold necklace provided by one of his standard-bearers, he later wore a jewel-studded diadem. Later emperors were crowned and acclaimed in a manner, until the momentous decision was taken to permit the Patriarch of Constantinople to physically place the crown on the emperors head. Historians debate when exactly this first took place, but the precedent was established by the reign of Leo II. This ritual included recitation of prayers by the Byzantine prelate over the crown, after this event, according to the Catholic Encyclopedia, the ecclesiastical element in the coronation ceremonial rapidly develop. This was usually performed three times, following this, the king was given a spear, and a diadem wrought of silk or linen was bound around his forehead as a token of regal authority
6.
Cleopatra Selene of Syria
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Cleopatra Selene I was the daughter of Ptolemy VIII Physcon by his niece Cleopatra III of Egypt. She was the wife of three different kings, including queen consort to Ptolemy IX Lathyros of Egypt, and later queen of Syria, originally she was named Selene, only adding the Ptolemaic throne name Cleopatra after her marriage with Lathyros. Whom she married after his wife, her sister Cleopatra IV, was forced out by her mother, Selene was not, however, made co-ruler, unlike many of the sister-wives of Ptolemaic kings. She bore Lathyros at least one daughter, Berenice III and two sons, including Ptolemy XII and possibly another son, also named Ptolemy. In the meantime, Cleopatra III established an alliance with one of the warring Syrian kings, Antiochus VIII Grypus, in Syria, the civil war between Grypus and Cyzicenus over the throne in Antioch lasted until 96 BC, when Grypus was assassinated in Antioch. Cyzicenus, after capturing the capital, married Cleopatra Selene I, Cyzicenus, however, was not to live much longer. Grypus had five sons with Cleopatra Tryphaena, all of competing for the throne of Antioch. In 95 BC, Cyzicenus was killed during a battle with Seleucus VI Epiphanes, after Cyzicenus death, his son with Cleopatra IV, Antiochus X Eusebes, married his stepmother, Cleopatra Selene I, and regained Antioch again, with the death of Seleucus VI. Cleopatra Selene I bore him two sons, Antiochus XIII Asiaticus and Seleucus Cybiosactes, Antiochus X was killed either in 92 BC in a battle with the Parthians, or in 83 BC. After his death Cleopatra Selene I, fearing for her safety, following the assassination of her nephew Ptolemy XI Alexander II, Cleopatra Selene I remained the only legitimate surviving member of the Ptolemaic dynasty. She claimed the throne of Egypt for her sons from her fourth marriage, Cleopatra Selene I sent her sons to Rome to present their claims before the senate, but they were unsuccessful, returning home two years later, possibly to Syria in late 73 and 72. Selene evidently ruled their Syrian possessions in their absence, controlling Ptolemais until 69, in 69 BC the Armenian king Tigranes the Great besieged Cleopatra Selene I in Ptolemais, seizing and brutally killing her in Seleucia. One year later, the Romans disrupted the Armenian state, and Cleopatra Selene Is son, Antiochus XIII, finally, in 63 BC, the Romans captured Syria and the Hellenistic state that Seleucus I Nicator created 240 years before, became part of Rome. List of Syrian monarchs Timeline of Syrian history Felix Stähelin, Kleopatra 22, in, Realencyclopädie der Classischen Altertumswissenschaft, vol. J. Whitehorne, Cleopatras,1994, pp. 164–173
7.
Dynasty
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A dynasty is a sequence of rulers from the same family, usually in the context of a feudal or monarchical system but sometimes also appearing in elective republics. The dynastic family or lineage may be known as a house, historians periodize the histories of many sovereign states, such as Ancient Egypt, the Carolingian Empire and Imperial China, using a framework of successive dynasties. As such, the dynasty may be used to delimit the era during which the family reigned and to describe events, trends. The word dynasty itself is often dropped from such adjectival references, until the 19th century, it was taken for granted that a legitimate function of a monarch was to aggrandize his dynasty, that is, to increase the territory, wealth, and power of his family members. The longest-surviving dynasty in the world is the Imperial House of Japan, dynasties throughout the world have traditionally been reckoned patrilineally, such as under the Frankish Salic law. Succession through a daughter when permitted was considered to establish a new dynasty in her husbands ruling house, however, some states in Africa, determined descent matrilineally, while rulers have at other times adopted the name of their mothers dynasty when coming into her inheritance. It is also extended to unrelated people such as poets of the same school or various rosters of a single sports team. The word dynasty derives via Latin dynastia from Greek dynastéia, where it referred to power, dominion and it was the abstract noun of dynástēs, the agent noun of dynamis, power or ability, from dýnamai, to be able. A ruler in a dynasty is referred to as a dynast. For example, following his abdication, Edward VIII of the United Kingdom ceased to be a member of the House of Windsor. A dynastic marriage is one that complies with monarchical house law restrictions, the marriage of Willem-Alexander, Prince of Orange, to Máxima Zorreguieta in 2002 was dynastic, for example, and their eldest child is expected to inherit the Dutch crown eventually. But the marriage of his younger brother Prince Friso to Mabel Wisse Smit in 2003 lacked government support, thus Friso forfeited his place in the order of succession, lost his title as a Prince of the Netherlands, and left his children without dynastic rights. In historical and monarchist references to formerly reigning families, a dynast is a member who would have had succession rights, were the monarchys rules still in force. Even since abolition of the Austrian monarchy, Max and his descendants have not been considered the rightful pretenders by Austrian monarchists, nor have they claimed that position. The term dynast is sometimes used only to refer to descendants of a realms monarchs. The term can therefore describe overlapping but distinct sets of people, yet he is not a male-line member of the royal family, and is therefore not a dynast of the House of Windsor. Thus, in 1999 he requested and obtained permission from Elizabeth II to marry the Roman Catholic Princess Caroline of Monaco. Yet a clause of the English Act of Settlement 1701 remained in effect at that time and that exclusion, too, ceased to apply on 26 March 2015, with retroactive effect for those who had been dynasts prior to triggering it by marriage to a Catholic
8.
Demetrius II Nicator
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For the similarly named Macedonian ruler, see Demetrius II of Macedon. For the Macedonian prince, see Demetrius the Fair, Demetrius II, called Nicator, was one of the sons of Demetrius I Soter, brother of Antiochus VII Sidetes and his mother could have been Laodice V. He ruled the Seleucid Empire for two periods, separated by a number of years of captivity in Hyrcania in Parthia. As a young boy, he fled to Crete after the death of his father, his mother and his older brother, about 147 BC he returned to Syria, and with the backing of Ptolemy VI Philometor, king of Egypt, regained his fathers throne. The Egyptian king also divorced his daughter Cleopatra Thea from Balas, Alexander fled to the Nabateans who, anxious to stay on good terms with Egypt, cut off his head. However, Demetrius was not a popular king, the people of Syria had little respect for the young boy, who had come to power with the help of Egypt and Cretan mercenaries led by the ruthless condottiere Lasthenes. The Antiochenians offered the Seleucid throne to Ptolemy VI, who had conquered most of southern Syria for his own interest. The Egyptian troops marched home, leaderless and disillusioned, and with Balas dead as well Demetrius became sole master of the Seleucid kingdom, the pillaging of the Cretan soldiers caused the Antiochenians to rise in rebellion, and only after terrible massacres was order restored. Soon after, the general Diodotus conquered Antioch and had his protégé Antiochus VI Dionysus, Demetrius proved unable to retake the capital, instead establishing himself in Seleucia. Diodotus had Antiochus VI deposed a few later, and made himself king as Tryphon. In 139 BC, Parthian activity forced Demetrius to take action and he marched against Mithradates I, king of Parthia and was initially successful, but was defeated in the Iranian mountains and taken prisoner the following year. King Mithradates had kept Demetrius II alive and even married him to a Parthian princess named Rhodogune, when the two friends were captured, the Parthian king did not punish Kallimander but rewarded him for his fidelity to Demetrius. The second time Demetrius was captured when he tried to escape, Mithradates humiliated him by giving him a set of dice. It was however for reasons that the Parthians treated Demetrius II kindly. In 130 BC Antiochus Sidetes felt secure enough to march against Parthia, now Phraates II made what he thought was a powerful move, he released Demetrius, hoping that the two brothers would start a civil war. However, Sidetes was defeated soon after his brothers release and never met him, Phraates II set people to pursue Demetrius, but he managed to safely return home to Syria and regained his throne and his queen as well. However, the Seleucid kingdom was now but a shadow of its former glory, recollections of his cruelties and vices – along with his humiliating defeat – caused him to be greatly detested. The Egyptian queen Cleopatra II set up an army for Demetrius, hoping to engage him in her wars against her brother king Ptolemy VIII
9.
Greece
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Greece, officially the Hellenic Republic, historically also known as Hellas, is a country in southeastern Europe, with a population of approximately 11 million as of 2015. Athens is the capital and largest city, followed by Thessaloniki. Greece is strategically located at the crossroads of Europe, Asia, situated on the southern tip of the Balkan peninsula, it shares land borders with Albania to the northwest, the Republic of Macedonia and Bulgaria to the north, and Turkey to the northeast. Greece consists of nine regions, Macedonia, Central Greece, the Peloponnese, Thessaly, Epirus, the Aegean Islands, Thrace, Crete. The Aegean Sea lies to the east of the mainland, the Ionian Sea to the west, the Cretan Sea and the Mediterranean Sea to the south. Greece has the longest coastline on the Mediterranean Basin and the 11th longest coastline in the world at 13,676 km in length, featuring a vast number of islands, eighty percent of Greece is mountainous, with Mount Olympus being the highest peak at 2,918 metres. From the eighth century BC, the Greeks were organised into various independent city-states, known as polis, which spanned the entire Mediterranean region and the Black Sea. Greece was annexed by Rome in the second century BC, becoming a part of the Roman Empire and its successor. The Greek Orthodox Church also shaped modern Greek identity and transmitted Greek traditions to the wider Orthodox World, falling under Ottoman dominion in the mid-15th century, the modern nation state of Greece emerged in 1830 following a war of independence. Greeces rich historical legacy is reflected by its 18 UNESCO World Heritage Sites, among the most in Europe, Greece is a democratic and developed country with an advanced high-income economy, a high quality of life, and a very high standard of living. A founding member of the United Nations, Greece was the member to join the European Communities and has been part of the Eurozone since 2001. Greeces unique cultural heritage, large industry, prominent shipping sector. It is the largest economy in the Balkans, where it is an important regional investor, the names for the nation of Greece and the Greek people differ from the names used in other languages, locations and cultures. The earliest evidence of the presence of human ancestors in the southern Balkans, dated to 270,000 BC, is to be found in the Petralona cave, all three stages of the stone age are represented in Greece, for example in the Franchthi Cave. Neolithic settlements in Greece, dating from the 7th millennium BC, are the oldest in Europe by several centuries and these civilizations possessed writing, the Minoans writing in an undeciphered script known as Linear A, and the Mycenaeans in Linear B, an early form of Greek. The Mycenaeans gradually absorbed the Minoans, but collapsed violently around 1200 BC and this ushered in a period known as the Greek Dark Ages, from which written records are absent. The end of the Dark Ages is traditionally dated to 776 BC, the Iliad and the Odyssey, the foundational texts of Western literature, are believed to have been composed by Homer in the 7th or 8th centuries BC. With the end of the Dark Ages, there emerged various kingdoms and city-states across the Greek peninsula, in 508 BC, Cleisthenes instituted the worlds first democratic system of government in Athens
10.
Alexander II Zabinas
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Alexander II Zabinas, ruler of the Greek Seleucid kingdom, was a counter-king who emerged in the chaos following the Seleucidian loss of Mesopotamia to the Parthians. Zabinas was a false Seleucid who claimed to be a son of Antiochus VII Sidetes. Antioch, Apamea, and several cities, disgusted with the tyranny of Demetrius. Zabinas fled to the Seleucid capital Antiochia, where he plundered several temples and he is said to have joked about melting down a statuette of the goddess of victory Nike which was held in the hand of a Zeus statue, saying Zeus has given me Victory. Enraged by his impiety the Antiochenes cast Zabinas out of the city and he soon fell into the hands of robbers, who delivered him up to Antiochus, by whom he was put to death, in 122 BC. The name Zabinas means the slave, and was applied to him, deprecatingly. For reasons unknown, Alexander II was the only late Seleucid not to use epithets on his coins, several of his coins are extant. List of Syrian monarchs Timeline of Syrian history
11.
Toxicology
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Toxicology is a branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms. It also studies the effects of chemical, biological and physical agents in biological systems that establishes the extent of damage in living organisms. The relationship between dose and its effects on the organism is of high significance in toxicology. Factors that influence chemical toxicity include the dosage, the route of exposure, dioscorides, a Greek physician in the court of the Roman emperor Nero, made the first attempt to classify plants according to their toxic and therapeutic effect. Ibn Wahshiyya wrote the Book on Poisons in the 9th or 10th century and this was followed up in 1360 by Khagendra Mani Darpana. Mathieu Orfila is considered the father of toxicology, having given the subject its first formal treatment in 1813 in his Traité des poisons. In 1850, Jean Stas became the first person to isolate plant poisons from human tissue. Theophrastus Phillipus Auroleus Bombastus von Hohenheim is also considered the father of toxicology and this is often condensed to, The dose makes the poison or in Latin Sola dosis facit venenum. The goal of toxicity assessment is to identify effects of a substance. Adverse effects depend on two factors, i) routes of exposure and ii) dose. To explore dose, substances are tested in both acute and chronic models, generally, different sets of experiments are conducted to determine whether a substance causes cancer and to examine other forms of toxicity. Factors that influence chemical toxicity, Dosage Both large single exposures, the classic experimental tool of toxicology is testing on non-human animals. As of 2014, such animal testing provides information that is not available by other means about how substances function in a living organism, while testing in animal models remains as a method of estimating human effects, there are both ethical and technical concerns with animal testing. This work requires expert knowledge in molecular modeling and statistics together with expert judgment in chemistry, pivotal events in science include the discovery of penicillin, the elucidation of the DNA double helix, and the development of computers. Toxicity testing is approaching such a scientific pivot point. It is poised to take advantage of the revolutions in biology and biotechnology, as of 2010 that vision was still unrealized. As of 2014 that vision was still unrealized, in some cases shifts away from animal studies has been mandated by law or regulation, the European Union prohibited use of animal testing for cosmetics in 2013. Most chemicals display a dose response curve – at a low dose. A few chemicals have no well-defined safe level of exposure and these are treated with special care
12.
Galen
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Aelius Galenus or Claudius Galenus, often Anglicized as Galen and better known as Galen of Pergamon, was a prominent Greek physician, surgeon and philosopher in the Roman Empire. The son of Aelius Nicon, an architect with scholarly interests, Galen received a comprehensive education that prepared him for a successful career as a physician. Galens understanding of anatomy and medicine was influenced by the then-current theory of humorism. His theories dominated and influenced Western medical science for more than 1,300 years, Medical students continued to study Galens writings until well into the 19th century. Galen saw himself as both a physician and a philosopher, as he wrote in his treatise entitled That the Best Physician is Also a Philosopher. Many of his works have been preserved and/or translated from the original Greek, although many were destroyed, although there is some debate over the date of his death, he was no younger than seventy when he died. In medieval Europe, Galens writings on anatomy became the mainstay of the medieval university curriculum. Some of Galens ideas were incorrect, he did not dissect a human body, Galens original Greek texts gained renewed prominence during the early modern period. In the 1530s, Belgian anatomist and physician Andreas Vesalius took on a project to many of Galens Greek texts into Latin. Vesaliuss most famous work, De humani corporis fabrica, was influenced by Galenic writing. Galens name Γαληνός, Galēnos comes from the adjective γαληνός, calm, Galen describes his early life in On the affections of the mind. Galen describes his father as an amiable, just, good. His studies also took in each of the philosophical systems of the time. His father had planned a career for Galen in philosophy or politics and took care to expose him to literary. However, Galen states that in around AD145 his father had a dream in which the god Asclepius appeared and commanded Nicon to send his son to study medicine, there he came under the influence of men like Aeschrion of Pergamon, Stratonicus and Satyrus. Asclepiea functioned as spas or sanitoria to which the sick would come to seek the ministrations of the priesthood, romans frequented the temple at Pergamon in search of medical relief from illness and disease. It was also the haunt of notable people such as Claudius Charax the historian, Aelius Aristides the orator, Polemo the sophist, in 148, when he was 19, his father died, leaving him independently wealthy. In 157, aged 28, he returned to Pergamon as physician to the gladiators of the High Priest of Asia, one of the most influential and wealthy men in Asia
13.
Zeus
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Zeus /ˈzjuːs/ is the sky and thunder god in ancient Greek religion, who ruled as king of the gods of Mount Olympus. His name is cognate with the first element of his Roman equivalent Jupiter and his mythologies and powers are similar, though not identical, to those of the Indo-European deities such as Indra, Jupiter, Perun, Thor, and Odin. Zeus is the child of Cronus and Rhea, the youngest of his siblings to be born, in most traditions, he is married to Hera, by whom he is usually said to have fathered Ares, Hebe, and Hephaestus. At the oracle of Dodona, his consort was said to be Dione, Zeus was also infamous for his erotic escapades. These resulted in many godly and heroic offspring, including Athena, Apollo, Artemis, Hermes, Persephone, Dionysus, Perseus, Heracles, Helen of Troy, Minos, and the Muses. He was equated with many foreign weather gods, permitting Pausanias to observe That Zeus is king in heaven is a common to all men. His symbols are the thunderbolt, eagle, bull, and oak, in addition to his Indo-European inheritance, the classical cloud-gatherer also derives certain iconographic traits from the cultures of the Ancient Near East, such as the scepter. Zeus is frequently depicted by Greek artists in one of two poses, standing, striding forward with a thunderbolt leveled in his right hand. The gods name in the nominative is Ζεύς Zeús and it is inflected as follows, vocative, Ζεῦ Zeû, accusative, Δία Día, genitive, Διός Diós, dative, Διί Dií. Diogenes Laertius quotes Pherecydes of Syros as spelling the name, Ζάς, Zeus is the Greek continuation of *Di̯ēus, the name of the Proto-Indo-European god of the daytime sky, also called *Dyeus ph2tēr. The god is known under this name in the Rigveda, Latin, Zeus is the only deity in the Olympic pantheon whose name has such a transparent Indo-European etymology. The earliest attested forms of the name are the Mycenaean Greek
14.
Nike (mythology)
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In ancient Greek religion, Nike was a goddess who personified victory. She was variously described as the daughter of the Titan Pallas and the goddess Styx, and the sister of Kratos, Bia, the word νίκη nikē is of uncertain etymology. R. S. P. Beekes has suggested a Pre-Greek origin, Nike and her siblings were close companions of Zeus, the dominant deity of the Greek pantheon. According to classical myth, Styx brought them to Zeus when the god was assembling allies for the Titanomachy against the older deities, Nike assumed the role of the divine charioteer, a role in which she often is portrayed in Classical Greek art. Nike flew around rewarding the victors with glory and fame. Nike is seen with wings in most statues and paintings, with one of the most famous being the Winged Victory of Samothrace, most other winged deities in the Greek pantheon had shed their wings by Classical times. Nike is the goddess of strength, speed, and victory, Nike was a very close acquaintance of Athena, and is thought to have stood in Athenas outstretched hand in the statue of Athena located in the Parthenon. Nike is also one of the most commonly portrayed figures on Greek coins, the sports equipment company Nike, Inc. is named after the Greek goddess Nike. Project Nike, an American anti-aircraft missile system is named after the goddess Nike, a figure of Nike with a vessel was the design of the first FIFA World Cup trophy, known also as the Jules Rimet trophy. Since Giuseppe Cassiolis design for the 1928 Summer Olympics, the face of every Olympic medal bears Nikes figure holding a palm frond in her right hand. The goddess appears on the emblem of the University of Melbourne, spirit of Ecstasy, the hood ornament used by the automobile manufacturer Rolls-Royce was inspired by Nike. The Titanic Engineers Memorial, Southampton depicts Nike blessing the engineers of the RMS Titanic for staying at their post as the ship sank, the Honda motorcycle companys logo is inspired by the goddess Nike. Winged Victory of Samothrace Altar of Victory Nike of Paeonius Ángel de la Independencia Smith, William, A Dictionary of Greek, online version at the Perseus Digital Library. Media related to Nike at Wikimedia Commons The dictionary definition of Nike at Wiktionary Theoi Project, Nike Goddess Nike
15.
Civil war
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The aim of one side may be to take control of the country or a region, to achieve independence for a region or to change government policies. The term is a calque of the Latin bellum civile which was used to refer to the civil wars of the Roman Republic in the 1st century BC. A civil war is a high-intensity conflict, often involving regular armed forces, Civil wars may result in large numbers of casualties and the consumption of significant resources. Most modern civil wars involve intervention by outside powers, according to Patrick M. Civil wars since the end of World War II have lasted on average just over four years, a dramatic rise from the one-and-a-half-year average of the 1900–1944 period. For example, there were no more than five civil wars underway simultaneously in the first half of the 20th century while there were over 20 concurrent civil wars close to the end of the Cold War. Since 1945, civil wars have resulted in the deaths of over 25 million people, ann Hironaka further specifies that one side of a civil war is the state. The intensity at which a civil disturbance becomes a war is contested by academics. Some political scientists define a civil war as having more than 1000 casualties, the Correlates of War, a dataset widely used by scholars of conflict, classifies civil wars as having over 1000 war-related casualties per year of conflict. Based on the 1000 casualties per year criterion, there were 213 civil wars from 1816 to 1997,104 of which occurred from 1944 to 1997. If one uses the less-stringent 1000 casualties total criterion, there were over 90 civil wars between 1945 and 2007, with 20 ongoing civil wars as of 2007. The Geneva Conventions do not specifically define the term civil war and this includes civil wars, however no specific definition of civil war is provided in the text of the Conventions. That the legal Government is obliged to have recourse to the military forces against insurgents organized as military. That the insurgents have an organization purporting to have the characteristics of a State and that the insurgent civil authority exercises de facto authority over the population within a determinate portion of the national territory. That the armed forces act under the direction of an authority and are prepared to observe the ordinary laws of war. That the insurgent civil authority agrees to be bound by the provisions of the Convention, scholars investigating the cause of civil war are attracted by two opposing theories, greed versus grievance. Scholarly analysis supports the conclusion that economic and structural factors are more important than those of identity in predicting occurrences of civil war, a comprehensive study of civil war was carried out by a team from the World Bank in the early 21st century. A second source of finance is national diasporas, which can fund rebellions, the study found that statistically switching the size of a countrys diaspora from the smallest found in the study to the largest resulted in a sixfold increase in the chance of a civil war. Opportunity cost of rebellion Higher male secondary school enrollment, per capita income, the study interpreted these three factors as proxies for earnings forgone by rebellion, and therefore that lower forgone earnings encourage rebellion
16.
Daphne
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Daphne is a minor figure in Greek mythology known as a naiad—a type of female nymph associated with fountains, wells, springs, streams, brooks and other bodies of freshwater. There are several versions of the myth, but the narrative is that because of her beauty, Daphne attracted the attention. Apollo pursued her and just before being overtaken, Daphne pleaded to her father, the rivergod Ladon, so Ladon then transformed Daphne into a laurel tree. In Metamorphoses by Roman poet Ovid, she is identified as the daughter of the rivergod Pineios in Thessaly. At the Pythian Games which were held four years in Delphi in honour of Apollo. According to Pausanias the reason for this simply and solely because the tradition has it that Apollo fell in love with the daughter of Ladon. According to Greek myth, Apollo chased the nymph Daphne, daughter of Peneus and Creusa in Thessaly, Ovid treats the encounter, Apollos lapse of majesty, in the mode of elegiac lovers, and expands the pursuit into a series of speeches. Only her shining beauty was left, why should she wish to escape. Most artistic impressions of the focus on the moment of transformation. A version of the attempt on Daphnes sworn virginity that has been less familiar since the Renaissance was narrated by the Hellenistic poet Parthenius, in his Erotica Pathemata, The Sorrows of Love. Parthenius tale, based on the Hellenistic historian Phylarchus, was known to Pausanias, at this moment Apollos attention becomes engaged, and he begins his own pursuit, Parthenius modern editor remarks on the rather awkward transition, linking two narratives. These genera are categorized in the family Thymelaeaceae and are native to Asia, Europe and North Africa. Artemis Daphnaia, who had her temple among the Lacedemonians, at a place called Hypsoi in Antiquity, Daphnes transformation in art Theoi Project, Daphne Apollo and Daphne – statue by Gian Lorenzo Bernini The Warburg Institute Iconographic Database, ca 200 images of Apollo and Daphne
17.
Antioch
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Antioch on the Orontes was an ancient Greco-Roman city on the eastern side of the Orontes River. Its ruins lie near the city of Antakya, Turkey. Antioch was founded near the end of the 4th century BC by Seleucus I Nicator, the citys geographical, military, and economic location benefited its occupants, particularly such features as the spice trade, the Silk Road, and the Persian Royal Road. It eventually rivaled Alexandria as the city of the Near East. It was also the center of Hellenistic Judaism at the end of the Second Temple period. Most of the development of Antioch was done during the Roman Empire. Antioch was called the cradle of Christianity as a result of its longevity, the Christian New Testament asserts that the name Christian first emerged in Antioch. It was one of the four cities of the Syrian tetrapolis, a single route proceeds south in the Orontes valley. The settlement of Meroe pre-dated Antioch, a shrine of the Semitic goddess Anat, called by Herodotus the Persian Artemis, was located here. This site was included in the suburbs of Antioch. There was a village on the spur of Mount Silpius named Io and this name was always adduced as evidence by Antiochenes anxious to affiliate themselves to the Attic Ionians—an eagerness which is illustrated by the Athenian types used on the citys coins. Io may have been an early colony of trading Greeks. John Malalas also mentions a village, Bottia, in the plain by the river. Macedonian ruler Alexander the Great is said to have camped on the site of Antioch and this account is found only in the writings of Libanius, a 4th-century orator from Antioch, and may be legend intended to enhance Antiochs status. But the story is not unlikely in itself, after Alexanders death in 323 BC, his generals divided up the territory he had conquered. Seleucus I Nicator won the territory of Syria, and he proceeded to found four sister cities in northwestern Syria, one of which was Antioch and he is reputed to have built sixteen Antiochs. Seleucus founded Antioch on a site chosen through ritual means, an eagle, the bird of Zeus, had been given a piece of sacrificial meat and the city was founded on the site to which the eagle carried the offering. Seleucus did this on the 22nd day of the month of Artemisios in the year of his reign
18.
Sandas
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Sandas was the Anatolian lion god during the Classical period. He used to be represented in association with a horned lion, sandan was often associated to the Greek god Herakles, and sometimes to Marduk. In ceremonies, an image of the god was placed inside a pyre and was set on fire, sandan appears in the coins of the Seleucids, as well as on other coins of Tarsus during the time of the Roman emperors
19.
Eagle
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Eagle is a common name for many large birds of prey of the family Accipitridae, it belongs to several groups of genera that are not necessarily closely related to each other. Most of the 60 species of eagles are from Eurasia and Africa, outside this area, just 14 species can be found – two in North America, nine in Central and South America, and three in Australia. Eagles are large, powerfully built birds of prey, with heavy heads, most eagles are larger than any other raptors apart from some vultures. The smallest species of eagle is the South Nicobar serpent eagle, the largest species are discussed below. Like all birds of prey, eagles have large, hooked beaks for ripping flesh from their prey, strong, muscular legs. The beak is typically heavier than that of most other birds of prey, Eagles eyes are extremely powerful, having up to 3.6 times human acuity for the martial eagle, which enables them to spot potential prey from a very long distance. This keen eyesight is primarily attributed to their extremely large pupils which ensure minimal diffraction of the incoming light, the female of all known species of eagles is larger than the male. Eagles normally build their nests, called eyries, in trees or on high cliffs. Many species lay two eggs, but the older, larger chick frequently kills its younger sibling once it has hatched, the dominant chick tends to be a female, as they are bigger than the male. The parents take no action to stop the killing, due to the size and power of many eagle species, they are ranked at the top of the food chain as apex predators in the avian world. The type of prey varies by genus, the snake and serpent eagles of the genera Circaetus, Terathopius, and Spilornis predominantly prey on the great diversity of snakes found in the tropics of Africa and Asia. The eagles of the genus Aquila are often the top birds of prey in open habitats, where Aquila eagles are absent, other eagles, such as the buteonine black-chested buzzard-eagle of South America, may assume the position of top raptorial predator in open areas. Many other eagles, including the species-rich Spizaetus genus, live predominantly in woodlands and these eagles often target various arboreal or ground-dwelling mammals and birds, which are often unsuspectingly ambushed in such dense, knotty environments. Hunting techniques differ among the species and genera, with some individual eagles having engaged in quite varied techniques based their environment, most eagles grab prey without landing and take flight with it, so the prey can be carried to a perch and torn apart. The bald eagle is noted for having flown with the heaviest load verified to be carried by any flying bird, golden and crowned eagles have killed ungulates weighing up to 30 kg and a martial eagle even killed a 37 kg duiker, 7–8 times heavier than the preying eagle. It has been observed that most birds of prey look back over their shoulders before striking prey, all hawks seem to have this habit, from the smallest kestrel to the largest Ferruginous – but not the Eagles. Among the eagles are some of the largest birds of prey, only the condors and it is regularly debated which should be considered the largest species of eagle. They could be measured variously in total length, body mass, different lifestyle needs among various eagles result in variable measurements from species to species
20.
Ptolemaic dynasty
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Their rule lasted for 275 years, from 305 to 30 BC. They were the last dynasty of ancient Egypt, Ptolemy, one of the seven somatophylakes who served as Alexander the Greats generals and deputies, was appointed satrap of Egypt after Alexanders death in 323 BC. In 305 BC, he declared himself Ptolemy I, later known as Sōter Saviour, the Egyptians soon accepted the Ptolemies as the successors to the pharaohs of independent Egypt. Ptolemys family ruled Egypt until the Roman conquest of 30 BC, all the male rulers of the dynasty took the name Ptolemy. Ptolemaic queens regnant, some of whom were the sisters of their husbands, were usually called Cleopatra, Arsinoe or Berenice. The most famous member of the line was the last queen, Cleopatra VII and her apparent suicide at the conquest by Rome marked the end of Ptolemaic rule in Egypt. Dates in brackets represent the dates of the Ptolemaic pharaohs. They frequently ruled jointly with their wives, who were also their sisters. Of these, one of the last and most famous was Cleopatra, several systems exist for numbering the later rulers, the one used here is the one most widely used by modern scholars. Arsinoe IV, in opposition to Cleopatra Ptolemy Keraunos - eldest son of Ptolemy I Soter, Ptolemy Apion - son of Ptolemy VIII Physcon. Ptolemy Philadelphus - son of Mark Antony and Cleopatra VII, Ptolemy of Mauretania - son of King Juba II of Numidia and Mauretania and Cleopatra Selene II, daughter of Cleopatra VII and Mark Antony. Contemporaries describe a number of the Ptolemaic dynasty members as extremely obese, whilst sculptures and coins reveal prominent eyes, familial Graves disease could explain the swollen necks and eye prominence, although this is unlikely to occur in the presence of morbid obesity. A. Lampela, Rome and the Ptolemies of Egypt, the development of their political relations 273-80 B. C. J. G. Manning, The Last Pharaohs, Egypt Under the Ptolemies, 305-30 BC. Livius. org, Ptolemies — by Jona Lendering
21.
Antiochus XII Dionysus
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Antiochus XII Dionysus, a ruler of the Greek Seleucid kingdom who reigned 87–84 BC. Antiochus XII was the son of Antiochus VIII Grypus and Tryphaena to take up the diadem. He succeeded his brother Demetrius III Eucaerus as separatist ruler of the parts of the last remaining Seleucid realms, basically Damascus. Antiochus initially gained support from Ptolemaic forces and was the last Seleucid ruler of any military reputation and he made several raids into the territories of the Jewish Hasmonean kings, and tried to check the rise of the Nabataean Arabs. The Battle of Cana against the latter turned out to be successful, until the young king was caught in a melee. Upon his death, the Syrian army fled and mostly perished in the desert, soon after, the Nabateans conquered Damascus. Antiochus titles - apart from Dionysos - mean respectively Manifest, Father-loving, the last Seleucid kings often used several epithets on their coins. List of Syrian monarchs Timeline of Syrian history Antiochus XII entry in historical sourcebook by Mahlon H. Smith
22.
Commagene
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The Kingdom of Commagene was an ancient Armenian kingdom of the Hellenistic period, located in and around the ancient city of Samosata, which served as its capital. The Iron Age name of Samosata, Kummuh, probably gives its name to Commagene, Commagene has been characterized as a buffer state between Armenia, Parthia, Syria, and Rome, culturally, it seems to have been correspondingly mixed. The territory of Commagene corresponds roughly to the modern Turkish provinces of Adıyaman, little is known of the region of Commagene prior to the beginning of the 2nd century BC. However, it seems that, from what little evidence remains and this control lasted until c. 163 BC, when the local satrap, Ptolemaeus of Commagene, established himself as independent ruler following the death of the Seleucid king, Antiochus IV Epiphanes. The Kingdom of Commagene maintained its independence until 17 AD, when it was made a Roman province by Emperor Tiberius, the reemergent state lasted until 72 AD, when the Emperor Vespasian finally and definitively made it part of the Roman Empire. It is now a World Heritage Site, the cultural identity of the Kingdom of Commagene has been variously characterized. Pierre Merlat suggests that the Commagenian city of Doliche, like others in its vicinity, was half Iranianized, david M. Lang describes Commagene as a former Armenian satellite kingdom, while Blömer and Winter call it a Hellenistic kingdom. Frank McLynn denominates it a a small Hellenised Armenian kingdom in southern Anatolia, while the language used on public monuments was typically Greek, Commagenes rulers made no secret of their Persian and Armenian affinities. Over the course of first centuries BC and AD, the names given on a tomb at Sofraz Köy show a mix of typical Hellenistic dynastic names with an introduction of Latin personal names. Lang notes the vitality of Graeco-Roman culture in Commagene, Commagene was originally a small Syro-Hittite kingdom, located in modern south-central Turkey, with its capital at Samosata. It was first mentioned in Assyrian texts as Kummuhu, which was normally an ally of Assyria, the Achaemenid Empire then conquered Commagene in the 6th century BC and Alexander the Great conquered the territory in the 4th century BC. Ptolemys dynasty was related to the Parthian kings, but his descendant Mithridates I Callinicus embraced Hellenistic culture and his dynasty could thus claim ties with both Alexander the Great and the Persian kings. This marriage may also have part of a peace treaty between Commagene and the Seleucid Empire. From this point on, the kingdom of Commagene became more Greek than Persian, with Sophene, it was to serve as an important centre for the transmission of Hellenistic and Roman culture in the region. Details are sketchy, but Mithridates Callinicus is thought have accepted Armenian suzerainty during the reign of Tigranes II the Great, Mithridates and Laodice’s son was King Antiochus I Theos of Commagene. Antiochus was an ally of the Roman general Pompey during the campaigns against Mithridates VI of Pontus in 64 BC. Thanks to his skills, Antiochus was able to keep Commagene independent from the Romans. In 17 when Antiochus III of Commagene died, Emperor Tiberius annexed Commagene to the province of Syria, in 38, Caligula reinstated Antiochus IIIs son Antiochus IV and also gave him the wild areas of Cilicia to govern
23.
Antiochus I Theos of Commagene
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Antiochus I Theos Dikaios Epiphanes Philorhomaios Philhellen was an Armenian king from the Kingdom of Commagene and the most famous king of that kingdom. The ruins of the tomb-sanctuary of Antiochus atop Mount Nemrut in Turkey were named to the UNESCO World Heritage list in 1987, several sandstone bas reliefs discovered at the site contain some of the oldest known images of two figures shaking hands. Antiochus I was the son and probably the child of King Mithridates I Callinicus. Antiochus was half Armenian, a distant member of the Orontid Dynasty, antiochus’ father Mithridates was the son of King of Commagene Sames II Theosebes Dikaios and an unidentified woman. More certain are his dynastic connections to the Diadochi, antiochus’ mother, Laodice VII Thea, was a Greek princess of the Seleucid Empire. Laodice’s father was the Seleucid King Antiochus VIII Grypus, while her mother was a Ptolemaic princess and these five men, the Diadochi successors, had served as generals under Macedonian King, Alexander the Great. Antiochus’ parents had married as part of an alliance between their kingdoms. Little is known of his life and education, aside from its philhellenic aspect, however, it seems that when his father died in 70 BC. Antiochus married Princess Isias Philostorgos of Cappadocia, daughter of King Ariobarzanes I of Cappadocia, Antiochus is first mentioned in the ancient sources in 69 BC, when Lucullus campaigned against the Armenian King Tigranes the Great. Antiochus made peace with the general Pompey in 64 BC, when Pompey successfully invaded Syria, Antiochus and Pompey then became allies. Antiochus in 59 BC was granted the toga praetexta and given official recognition from the Roman Senate as an ally to Rome, Antiochus received an ivory sceptre and an embroidered triumphal robe, and he was greeted as king, ally and friend. This recognition was a way of recognising and rewarding the allies to Rome. From his reign onwards, monarchs from Commagene proved to be the most loyal Roman allies, when Marcus Tullius Cicero was Roman governor of Cilicia in 51 BC, Antiochus provided Cicero with intelligence of the movements of the Parthians. During the civil war between Julius Caesar and Pompey, Antiochus provided troops for Pompey, in 38 BC, a legate of Triumvir Mark Antony, Publius Ventidius Bassus, after campaigning against the Parthians, wanted to attack Antiochus and his kingdom. Antony and Bassus were attracted by Commagenes wealth, yet as they were preparing to march against Commagene and its capital Samosata, Antiochus negotiated a peaceful settlement with them. Antiochus is famous for building the impressive religious sanctuary of Nemrud Dagi or Mount Nemrut, when Antiochus reigned as king he was creating a royal cult for himself and preparing to be worshipped after his death. Antiochus was inspired to create his own cult in the Greek form of the religion Zoroastrianism, Antiochus left many Greek inscriptions revealing many aspects of his religion and explaining his purpose of action. In one inscription, Antiochus directed that his tomb should be built in a high and holy place, remote from people and close to the gods, Antiochus wanted his body to be preserved for eternity
24.
Cleopatra III of Egypt
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Cleopatra III was a queen of Egypt 142–101 BC. Cleopatra III was also known as Cleopatra Euergetis while associated with her husband Ptolemy VIII or her son Ptolemy X and she is attested as Cleopatra Philometor Soteira while associated with her eldest son Ptolemy IX. But he was forced to abdicate. Cleopatra III’s parents retook the throne and remained in power for almost 20 years until 145 BC and it was during this time that Cleopatra III was born, a sister of Ptolemy Eupator, Cleopatra Thea and possibly Berenice. Ptolemy VIII first married Cleopatra III’s mother Cleopatra II in 145 BC, Cleopatra II rebelled against Ptolemy VIII in c.132 BC and Cleopatra III fled to Cyprus in 130 BC with her husband, but was able to return to Alexandria in 127 BC. Cleopatra III and Ptolemy VIII had five children, Ptolemy IX born c.143 BC Tryphaena born c.141 BC, married Antiochus VIII Grypus, king of Syria in 124 BC Ptolemy X born c.140 or 139 BC. Married his niece Berenice Cleopatra IV born between 138 and 135 BC, married first her brother Ptolemy IX and second Antiochus IX Cyzicenus, king of Syria Cleopatra Selene I born between 135 and 130 BC. Married first to her brother Ptolemy IX, and later to her brother Ptolemy X, after the death of Ptolemy VIII in 116 BC Cleopatra III ruled jointly with her mother Cleopatra II and her son Ptolemy IX. Cleopatra III expelled Ptolemy IX from Alexandria in 107 BC and replaced him as co-regent with her second son Ptolemy X, after 6 years of joint rule Ptolemy X had his mother Cleopatra III murdered in 101 BC
25.
International Standard Book Number
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The International Standard Book Number is a unique numeric commercial book identifier. An ISBN is assigned to each edition and variation of a book, for example, an e-book, a paperback and a hardcover edition of the same book would each have a different ISBN. The ISBN is 13 digits long if assigned on or after 1 January 2007, the method of assigning an ISBN is nation-based and varies from country to country, often depending on how large the publishing industry is within a country. The initial ISBN configuration of recognition was generated in 1967 based upon the 9-digit Standard Book Numbering created in 1966, the 10-digit ISBN format was developed by the International Organization for Standardization and was published in 1970 as international standard ISO2108. Occasionally, a book may appear without a printed ISBN if it is printed privately or the author does not follow the usual ISBN procedure, however, this can be rectified later. Another identifier, the International Standard Serial Number, identifies periodical publications such as magazines, the ISBN configuration of recognition was generated in 1967 in the United Kingdom by David Whitaker and in 1968 in the US by Emery Koltay. The 10-digit ISBN format was developed by the International Organization for Standardization and was published in 1970 as international standard ISO2108, the United Kingdom continued to use the 9-digit SBN code until 1974. The ISO on-line facility only refers back to 1978, an SBN may be converted to an ISBN by prefixing the digit 0. For example, the edition of Mr. J. G. Reeder Returns, published by Hodder in 1965, has SBN340013818 -340 indicating the publisher,01381 their serial number. This can be converted to ISBN 0-340-01381-8, the check digit does not need to be re-calculated, since 1 January 2007, ISBNs have contained 13 digits, a format that is compatible with Bookland European Article Number EAN-13s. An ISBN is assigned to each edition and variation of a book, for example, an ebook, a paperback, and a hardcover edition of the same book would each have a different ISBN. The ISBN is 13 digits long if assigned on or after 1 January 2007, a 13-digit ISBN can be separated into its parts, and when this is done it is customary to separate the parts with hyphens or spaces. Separating the parts of a 10-digit ISBN is also done with either hyphens or spaces, figuring out how to correctly separate a given ISBN number is complicated, because most of the parts do not use a fixed number of digits. ISBN issuance is country-specific, in that ISBNs are issued by the ISBN registration agency that is responsible for country or territory regardless of the publication language. Some ISBN registration agencies are based in national libraries or within ministries of culture, in other cases, the ISBN registration service is provided by organisations such as bibliographic data providers that are not government funded. In Canada, ISBNs are issued at no cost with the purpose of encouraging Canadian culture. In the United Kingdom, United States, and some countries, where the service is provided by non-government-funded organisations. Australia, ISBNs are issued by the library services agency Thorpe-Bowker
26.
King of Syria
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The title King of Syria and Queen of Syria appeared in the second century BC in referring to the Seleucid kings who ruled the entirety of the region of Syria. It was also used to refer to Aramean kings in the Greek translations of the Old Testament, mainly indicating the kings of Aram-Damascus. Following the defeat of the in World War I, the region came under the rule of France, United Kingdom, faisals reign lasted a few months before he was overthrown by France and the title fell out of use. The term Syria was first applied by Herodotus in the 5th century BC to indicate a region generally extending between Anatolia and Egypt, with the advent of the Hellenistic period, Greeks and their Seleucid dynasty used the term Syria to designate the region between the Mediterranean and the Euphrates. The usage of the name in referring to the region during the Iron Age is a modern practice, starting from the 2nd century BC, ancient writers, such as Polybius and Posidonius, began referring to the Seleucid ruler as the king of Syria. The evidence for this usage by the kings is provided by the inscription of Antigonus son of Menophilus. Faisal was expelled from Syria on 25 July and went into exile in the United Kingdom, on 10 August, the Treaty of Sèvres divided the region into League of Nations mandates governed by France and the United Kingdom. Aram in the Hebrew Old Testament and Syria in the translation indicated the kingdom of Aram-Damascus most of the times. According to W. Edward Glenny, the rendering of Aram by Syria might be explained by a bias, since at the time of the translation, Syria belonged to the Seleucids. Aram-Damascus was the Jews enemy during its Iron Age prime in the 9th century BC, greater Syria Syrian nationalism List of Seleucid rulers History of Syria
27.
Hellenistic period
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It is often considered a period of transition, sometimes even of decadence or degeneration, compared to the enlightenment of the Greek Classical era. The Hellenistic period saw the rise of New Comedy, Alexandrian poetry, the Septuagint, Greek science was advanced by the works of the mathematician Euclid and the polymath Archimedes. The religious sphere expanded to include new gods such as the Greco-Egyptian Serapis, eastern deities such as Attis and Cybele, the Hellenistic period was characterized by a new wave of Greek colonization which established Greek cities and kingdoms in Asia and Africa. This resulted in the export of Greek culture and language to new realms. Equally, however, these new kingdoms were influenced by the cultures, adopting local practices where beneficial, necessary. Hellenistic culture thus represents a fusion of the Ancient Greek world with that of the Near East, Middle East and this mixture gave rise to a common Attic-based Greek dialect, known as Koine Greek, which became the lingua franca through the Hellenistic world. Scholars and historians are divided as to what event signals the end of the Hellenistic era, Hellenistic is distinguished from Hellenic in that the first encompasses the entire sphere of direct ancient Greek influence, while the latter refers to Greece itself. The word originated from the German term hellenistisch, from Ancient Greek Ἑλληνιστής, from Ἑλλάς, Hellenistic is a modern word and a 19th-century concept, the idea of a Hellenistic period did not exist in Ancient Greece. Although words related in form or meaning, e. g, the major issue with the term Hellenistic lies in its convenience, as the spread of Greek culture was not the generalized phenomenon that the term implies. Some areas of the world were more affected by Greek influences than others. The Greek population and the population did not always mix, the Greeks moved and brought their own culture. While a few fragments exist, there is no surviving historical work which dates to the hundred years following Alexanders death. The works of the major Hellenistic historians Hieronymus of Cardia, Duris of Samos, the earliest and most credible surviving source for the Hellenistic period is Polybius of Megalopolis, a statesman of the Achaean League until 168 BC when he was forced to go to Rome as a hostage. His Histories eventually grew to a length of forty books, covering the years 220 to 167 BC, another important source, Plutarchs Parallel Lives though more preoccupied with issues of personal character and morality, outlines the history of important Hellenistic figures. Appian of Alexandria wrote a history of the Roman empire that includes information of some Hellenistic kingdoms, other sources include Justins epitome of Pompeius Trogus Historiae Philipicae and a summary of Arrians Events after Alexander, by Photios I of Constantinople. Lesser supplementary sources include Curtius Rufus, Pausanias, Pliny, in the field of philosophy, Diogenes Laertius Lives and Opinions of Eminent Philosophers is the main source. Ancient Greece had traditionally been a collection of fiercely independent city-states. After the Peloponnesian War, Greece had fallen under a Spartan hegemony, in which Sparta was pre-eminent but not all-powerful
28.
Argead dynasty
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The Argead dynasty was an ancient Greek royal house. They were the founders and the dynasty of Macedon from about 700 to 310 BC. Their tradition, as described in ancient Greek historiography, traced their origins to Argos, initially the rulers of the homonymous tribe, by the time of Philip II they had expanded their reign further, to include under the rule of Macedonia all Upper Macedonian states. The mythical founder of the Argead dynasty is King Caranus, the words Argead and Argive derive from the Greek Ἀργεῖος, of or from Argos, which is first attested in Homer, where it was also used as a collective designation for the Greeks. The Argead dynasty claimed descent from the Temenids of Argos, in the Peloponnese, whose ancestor was Temenus. In the excavations of the royal Palace at Aegae Manolis Andronikos discovered in the room an inscription relating to that belief. The latter asked them to leave his territory, believing in an omen that something great would happen to Perdiccas, the boys went to another part of Macedonia, near the garden of Midas, above which mount Bermio stands. There they made their abode and gradually formed their own kingdom, the Hellanodikai, however, after examining his Argead claim confirmed that the Macedonians were Greeks and allowed him to participate. They also added Mygdonia in their territory through the expulsion of the Edoni, Eordians, the Kings of Makedon, 399–369 BC. Archived from the original on 26 April 2008
29.
Philip II of Macedon
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Philip II of Macedon was the king of the Ancient Greek kingdom of Macedon from 359 BC until his assassination in 336 BC. He was a member of the Argead dynasty of Macedonian kings, the son of King Amyntas III. However, his assassination led to the succession of his son Alexander. Philip was the youngest son of the king Amyntas III and Eurydice I, in his youth, Philip was held as a hostage in Thebes, which was then the leading city of Greece. In 364 BC, Philip returned to Macedon, the deaths of Philips elder brothers, King Alexander II and Perdiccas III, allowed him to take the throne in 359 BC. Originally appointed regent for his infant nephew Amyntas IV, who was the son of Perdiccas III, Philips military skills and expansionist vision of Macedonian greatness brought him early success. He first had to remedy a predicament which had greatly worsened by the defeat against the Illyrians in which King Perdiccas himself had died. Using diplomacy, Philip pushed back the Paionians and Thracians promising tributes, momentarily free from his opponents, he concentrated on strengthening his internal position and, above all, his army. Philip had married Audata, great-granddaughter of the Illyrian king of Dardania, however, this did not prevent him from marching against the Illyrians in 358 and crushing them in a ferocious battle in which some 7,000 Illyrians died. By this move, Philip established his authority inland as far as Lake Ohrid, the Athenians had been unable to conquer Amphipolis, which commanded the gold mines of Mount Pangaion. So Philip reached an agreement with Athens to lease the city to them after its conquest, however, after conquering Amphipolis, Philip kept both cities. As Athens had declared war against him, he allied Macedon with the Chalkidian League of Olynthus and he subsequently conquered Potidaea, this time keeping his word and ceding it to the League in 356. In 357 BC, Philip married the Epirote princess Olympias, who was the daughter of the king of the Molossians, Alexander was born in 356, the same year as Philips racehorse won at the Olympic Games. During 356 BC, Philip conquered the town of Crenides and changed its name to Philippi and he then established a powerful garrison there to control its mines, which yielded much of the gold he later used for his campaigns. In the meantime, his general Parmenion defeated the Illyrians again, in 355–354 he besieged Methone, the last city on the Thermaic Gulf controlled by Athens. During the siege, Philip was injured in his eye, despite the arrival of two Athenian fleets, the city fell in 354. Philip also attacked Abdera and Maronea, on the Thracian coast, Philip was involved in the Third Sacred War which had begun in Greece in 356. In summer 353 he invaded Thessaly, defeating 7,000 Phocians under the brother of Onomarchus, the latter however defeated Philip in the two succeeding battles
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Alexander the Great
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Alexander III of Macedon, commonly known as Alexander the Great, was a king of the Ancient Greek kingdom of Macedon and a member of the Argead dynasty. He was born in Pella in 356 BC and succeeded his father Philip II to the throne at the age of twenty and he was undefeated in battle and is widely considered one of historys most successful military commanders. During his youth, Alexander was tutored by Aristotle until the age of 16, after Philips assassination in 336 BC, he succeeded his father to the throne and inherited a strong kingdom and an experienced army. Alexander was awarded the generalship of Greece and used this authority to launch his fathers Panhellenic project to lead the Greeks in the conquest of Persia, in 334 BC, he invaded the Achaemenid Empire and began a series of campaigns that lasted ten years. Following the conquest of Anatolia, Alexander broke the power of Persia in a series of battles, most notably the battles of Issus. He subsequently overthrew Persian King Darius III and conquered the Achaemenid Empire in its entirety, at that point, his empire stretched from the Adriatic Sea to the Indus River. He sought to reach the ends of the world and the Great Outer Sea and invaded India in 326 BC and he eventually turned back at the demand of his homesick troops. Alexander died in Babylon in 323 BC, the city that he planned to establish as his capital, without executing a series of planned campaigns that would have begun with an invasion of Arabia. In the years following his death, a series of civil wars tore his empire apart, resulting in the establishment of several states ruled by the Diadochi, Alexanders surviving generals, Alexanders legacy includes the cultural diffusion which his conquests engendered, such as Greco-Buddhism. He founded some twenty cities that bore his name, most notably Alexandria in Egypt, Alexander became legendary as a classical hero in the mold of Achilles, and he features prominently in the history and mythic traditions of both Greek and non-Greek cultures. He became the measure against which military leaders compared themselves, and he is often ranked among the most influential people in human history. He was the son of the king of Macedon, Philip II, and his wife, Olympias. Although Philip had seven or eight wives, Olympias was his wife for some time. Several legends surround Alexanders birth and childhood, sometime after the wedding, Philip is said to have seen himself, in a dream, securing his wifes womb with a seal engraved with a lions image. Plutarch offered a variety of interpretations of dreams, that Olympias was pregnant before her marriage, indicated by the sealing of her womb. On the day Alexander was born, Philip was preparing a siege on the city of Potidea on the peninsula of Chalcidice. That same day, Philip received news that his general Parmenion had defeated the combined Illyrian and Paeonian armies, and it was also said that on this day, the Temple of Artemis in Ephesus, one of the Seven Wonders of the World, burnt down. This led Hegesias of Magnesia to say that it had burnt down because Artemis was away, such legends may have emerged when Alexander was king, and possibly at his own instigation, to show that he was superhuman and destined for greatness from conception
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Philip III of Macedon
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Philip III Arrhidaeus reigned as king of Macedonia from after 11 June 323 BC until his death. He was a son of King Philip II of Macedonia by Philinna of Larissa, named Arrhidaeus at birth, he assumed the name Philip when he ascended to the throne. As Arrhidaeus grew older it became apparent that he had learning difficulties. Alexander was fond of Arrhidaeus and took him on his campaigns, after Alexanders death in Babylon in 323 BC, the Macedonian army in Asia proclaimed Arrhidaeus as king, however, he served merely as a figurehead and as the pawn of a series of powerful generals. Arrhidaeus whereabouts during the reign of his brother Alexander are unclear from the extant sources and he was in Babylon at the time of Alexanders death on 10 June 323 BC. Arrhidaeus was the most obvious candidate, but he was unfit to rule. This eventuality did indeed arise and resulted in Roxanas son, Alexander and it was immediately decided that Philip Arrhidaeus would reign, but not rule, this was to be the prerogative of the new regent, Perdiccas. When news arrived in Macedonia that Arrhidaeus had been chosen as king, Cynane and this move was an obvious affront to the regent, whom Cynane had completely bypassed, and to prevent the marriage, Perdiccas sent his brother, Alcetas, to kill Cynane. The reaction among the troops generated by this murder was such that the regent had to give up his opposition to the proposed match and accept the marriage. From that moment on, Philip Arrhidaeus was to be under the sway of his bride, eurydices chance to increase her husbands power came when the first war of the Diadochi sealed the fate of Perdiccas, making a new settlement necessary. An agreement was made at Triparadisus in Syria in 320 BC, the regent died of natural causes the following year, nominating as his successor not his son Cassander, but his friend and lieutenant, Polyperchon. Cassanders refusal to accept his fathers decision sparked the Second War of the Diadochi, an opportunity presented itself in 317 BC when Cassander expelled Polyperchon from Macedonia. Eurydice immediately allied herself with Cassander and persuaded her husband to him as the new regent. Cassander reciprocated by leaving her in control of the country when he left to campaign in Greece. But individual circumstances and events at time were subject to rapid change. That same year, Polyperchon and Olympias allied with her cousin, Aeacides, king of Epirus, the Macedonian troops refused to fight Olympias, the mother of Alexander. Philip and Eurydice had no choice but to escape, only to be captured at Amphipolis, in 1977, important excavations were made near Vergina leading to the discovery of a two-chambered royal tomb, with an almost perfectly preserved male skeleton. He appears as one of the characters in the novel Funeral Games by Mary Renault
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Alexander IV of Macedon
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Alexander IV, erroneously called sometimes in modern times Aegus, was the son of Alexander the Great and Princess Roxana of Bactria. Alexander IV was the son of a Macedonian father, Alexander the Great and he was Philip II of Macedons grandson. Because Roxana was pregnant when her died and the sex of the baby was unknown. The factions compromised, deciding that Perdiccas would rule the Empire as regent while Philip would reign, if the child was male, then he would be king. Alexander IV was born in August,323 BC and he brought with him Roxana and the two kings to Macedon and gave up the pretence of ruling Alexanders Empire, leaving former provinces in Egypt and Asia in control of the satraps. When Antipater died in 319 BC he left Polyperchon, a Macedonian general who had served under Philip II and Alexander the Great, as his successor, passing over his own son, Cassander. Cassander allied himself with Ptolemy Soter, Antigonus and Eurydice, the wife of king Philip Arrhidaeus. Polyperchon was allied with Eumenes and Olympias, although Polyperchon was successful at first, taking control of the Greek cities, his fleet was destroyed by Antigonus in 318 BC. When, after the battle, Cassander assumed full control of Macedon, Polyperchon was forced to flee to Epirus, followed by Roxana, a few months later, Olympias was able to persuade her relative Aeacides of Epirus to invade Macedon with Polyperchon. When Olympias took the field, Eurydices army refused to fight against the mother of Alexander and defected to Olympias, after which Polyperchon and Aeacides retook Macedon. Philip and Eurydice were captured and executed on December 25,317 BC, leaving Alexander IV king, Cassander returned in the following year, conquering Macedon once again. Olympias was immediately executed, while the king and his mother were taken prisoner, cassanders response was definitive, to secure his rule, in 309 BC he commanded Glaucias to secretly assassinate the 14-year-old Alexander IV and his mother. The orders were carried out, and they were both poisoned, one of the royal tombs discovered by the archaeologist Manolis Andronikos in the so-called Great Tumulus in Vergina in 1977/8 is believed to belong to Alexander IV. Smith, William, Dictionary of Greek and Roman Biography and Mythology, Alexander IV, livius. org, Alexander IV Wiki Classical Dictionary, Alexander IV
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Antigonid dynasty
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The Antigonid dynasty was a dynasty of Hellenistic kings descended from Alexander the Greats general Antigonus I Monophthalmus. Succeeding the Antipatrid dynasty in much of Macedonia, Antigonus ruled mostly over Asia Minor and his attempts to take control of the whole of Alexanders empire led to his defeat and death at the Battle of Ipsus in 301 BC. After a period of confusion, Demetriuss son Antigonus II Gonatas was able to establish the control over the old Kingdom of Macedon, as well as over most of the Greek city-states. It was one of four established by Alexanders successors, the others being the Seleucid dynasty, Ptolemaic dynasty. The ruling members of the Antigonid dynasty were, The Greek rebel against Rome and last King of Macedonia, Andriscus, claimed to be the son of Perseus
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Antigonus I Monophthalmus
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Antigonus I Monophthalmus, son of Philip from Elimeia, was a Macedonian nobleman, general, and satrap under Alexander the Great. During his early life he served under Philip II, and he was a figure in the Wars of the Diadochi after Alexanders death, declaring himself king in 306 BC. Antigonus was appointed governor of Greater Phrygia in 333 BC and he was primarily responsible for defending Alexanders lines of supply and communication during the latters extended campaign against the Achaemenid Persian Empire. As part of the division of the provinces after Alexanders death in 323 BC, Antigonus also received Pamphylia and Lycia from Perdiccas, regent of the empire, at the Partition of Babylon. He incurred the enmity of Perdiccas, the regent, by refusing to assist Eumenes to obtain possession of the allotted to him. Leonnatus had left with his army for Greece, leaving Antigonus alone to deal with Cappadocia, Perdiccas seems to have viewed this as a direct affront to his authority and went up with the royal army himself to conquer the area. Eumenes was defeated and forced to retire to the fortress of Nora in Cappadocia, when Antipater died in 319 BC, he gave the regentship to Polyperchon, excluding Cassander, his son. Antigonus and the other refused to recognize Polyperchon, since it would undermine their own ambitions. He entered into negotiations with Eumenes, but Eumenes had already been swayed by Polyperchon, effecting his escape from Nora, he raised an army and built a fleet in Cilicia and Phoenicia, and soon after formed a coalition with the satraps of the eastern provinces. Antigonus fought against Eumenes in two battles at Paraitacene in 317 BC and Gabiene in 316 BC. After some deliberation, Antigonus had Eumenes executed, as a result, Antigonus now was in possession of the empires Asian territories, his authority stretching from the eastern satrapies to Syria and Asia Minor in the west. He seized the treasures at Susa and entered Babylon, the governor of the city, Seleucus, fled to Ptolemy and entered into a league with him, Lysimachus and Cassander against Antigonus. In 314 BC Antigonus invaded Phoenicia, under Ptolemys control, and his son Demetrius was defeated at the Battle of Gaza by Ptolemy in 312 BC, and after the battle, Seleucus made his way back to Babylonia. Seleucus returned to Babylon in order to build up a base of his own, the Babylonian War began between Antigonus and Seleucus, where Seleucus defeated both Demetrius and Antigonus, and secured Babylonia. After the war had been carried on with varying success from 315 to 311, peace was concluded, by which the government of Asia Minor and Syria was provisionally secured to Antigonus. This agreement was violated on the pretext that garrisons had been placed in some of the free Greek cities by Antigonus. Demetrius Poliorcetes, the son of Antigonus, wrested part of Greece from Cassander, after defeating Ptolemy at the naval Battle of Salamis in 306 BC, Demetrius conquered Cyprus. Following the victory Antigonus assumed the title king and bestowed the same upon his son, the other dynasts, Cassander, Ptolemy, Lysimachus and Seleucus, soon followed
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Demetrius I of Macedon
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Demetrius I, called Poliorcetes, son of Antigonus I Monophthalmus and Stratonice, was a Macedonian Greek nobleman, military leader, and finally king of Macedon. He belonged to the Antigonid dynasty and was its first member to rule Macedonia, at the age of twenty-two he was left by his father to defend Syria against Ptolemy the son of Lagus. He was defeated at the Battle of Gaza, but soon partially repaired his loss by a victory in the neighbourhood of Myus. In the spring of 310, he was defeated when he tried to expel Seleucus I Nicator from Babylon. As a result of this Babylonian War, Antigonus lost almost two thirds of his empire, all eastern satrapies fell to Seleucus, after several campaigns against Ptolemy on the coasts of Cilicia and Cyprus, Demetrius sailed with a fleet of 250 ships to Athens. He freed the city from the power of Cassander and Ptolemy, expelled the garrison which had been stationed there under Demetrius of Phalerum, after these victories he was worshipped by the Athenians as a tutelary deity under the title of Soter. In the campaign of 306 BC he defeated Ptolemy and Menelaus, Ptolemys brother, in the naval Battle of Salamis, Demetrius conquered Cyprus in 306 BC, capturing one of Ptolemys sons. Following the victory Antigonus assumed the title king and bestowed the same upon his son Demetrius, in 302 BC he returned a second time to Greece as liberator, and reinstated the Corinthian League, but his licentiousness and extravagance made the Athenians long for the government of Cassander. Among his outrages was his courtship of a boy named Democles the Handsome. The youth kept on refusing his attention but one day found himself cornered at the baths, having no way out and being unable to physically resist his suitor, he took the lid off the hot water cauldron and jumped in. His death was seen as a mark of honor for himself, in another instance, Demetrius waived a fine of 50 talents imposed on a citizen in exchange for the favors of Cleaenetus, that mans son. He also sought the attention of Lamia, a Greek courtesan and he demanded 250 talents from the Athenians, which he then gave to Lamia and other courtesans to buy soap and cosmetics. He also roused the jealousy of Alexanders Diadochi, Seleucus, Cassander and Lysimachus united to destroy him, the hostile armies met at the Battle of Ipsus in Phrygia. Antigonus was killed, and Demetrius, after sustaining severe losses and this reversal of fortune stirred up many enemies against him—the Athenians refused even to admit him into their city. But he soon afterwards ravaged the territory of Lysimachus and effected a reconciliation with Seleucus, in 294 he established himself on the throne of Macedonia by murdering Alexander V, the son of Cassander. He faced rebellion from the Boeotians but secured the region after capturing Thebes in 291 BC, after besieging Athens without success he passed into Asia and attacked some of the provinces of Lysimachus with varying success. Famine and pestilence destroyed the part of his army, and he solicited Seleucus support. His son Antigonus offered all his possessions, and even his own person, in order to procure his fathers liberty, but all proved unavailing and his remains were given to Antigonus and honoured with a splendid funeral at Corinth
