The Arauco War was a long-running conflict between colonial Spaniards and the Mapuche people, mostly fought in the Araucanía region of Chile. The conflict began at first as a reaction to the Spanish conquerors attempting to establish cities and force Mapuches into servitude. It subsequently evolved over time into phases comprising drawn-out sieges, slave-hunting expeditions, pillaging raids, punitive expeditions, and renewed Spanish attempts to secure lost territories. Abduction of women and war rape was common on both sides.

Santiago, also known as Santiago de Chile, is the capital and largest city of Chile and one of the largest cities in the Americas. It is located in the country's central valley and is the center of the Santiago Metropolitan Region, which has a population of seven million, representing 40% of Chile's total population. Most of the city is situated between 500–650 m (1,640–2,133 ft) above sea level.