Arkansas Highway 133 is a designation for three state highways in South Arkansas. One route of 24.20 miles (38.95 km) runs from Louisiana Highway 142 north through Crossett to Highway 8 near Fountain Hill. A second segment runs from Highway 160 north to US Route 425 (US 425) at Lacey. A third segment begins in Rison at Highway 35 and runs north to Highway 54 south of Pine Bluff.

Highway 160 is a designation for four state highways in South Arkansas. The northernmost segment of 51.55 miles (82.96 km) runs from Farm to Market Road 249 at the Texas state line near Bloomburg, Texas east to Highway 19 at Macedonia. A second segment of 14.73 miles (23.71 km) runs east from Highway 57 east to Highway 7 Business in Smackover. In southern Calhoun County, Highway 160 begins at US Route 278 (US 278) and runs east to US 425 in Fountain Hill. A fourth segment begins at US 82 and runs 22.73 miles (36.58 km) east to US 65 at Chicot Junction.