The Elizabeth Arkham Asylum for the Criminally Insane, commonly referred to as Arkham Asylum, is a fictional psychiatric hospital/prison, appearing in American comic books published by DC Comics, commonly in stories featuring the superhero Batman. It first appeared in Batman #258, written by Dennis O'Neil with art by Irv Novick. The asylum serves as a (forensic) psychiatric hospital for the Gotham City area, housing patients who are criminally insane, as well as select prisoners with unusual medical requirements that are beyond a conventional prison's ability to accommodate. Its high-profile patients are often members of Batman's rogues gallery.

Arkham is a fictional city situated in Massachusetts, United States. An integral part of the Lovecraft Country setting created by H. P. Lovecraft, Arkham is featured in many of his stories and those of other Cthulhu Mythos writers.