Asclepiades, sometimes called Asclepiades of Bithynia or Asclepiades of Prusa, was a Greek physician born at Prusias-on-Sea in Bithynia in Anatolia and who flourished at Rome, where he practised and taught Greek medicine. He attempted to build a new theory of disease, based on the flow of "atoms" through pores in the body. His treatments sought to restore harmony through the use of diet, exercise, and bathing.
Bust of Asclepiades
Bithynia was an ancient region, kingdom and Roman province in the northwest of Asia Minor, adjoining the Sea of Marmara, the Bosporus, and the Black Sea. It bordered Mysia to the southwest, Paphlagonia to the northeast along the Pontic coast, and Phrygia to the southeast towards the interior of Asia Minor.
The Constantinople Gate in Nicaea