The athletics competition at the 1991 All-Africa Games was held from 23–27 September 1991 in Cairo, Egypt.

Frank "Frankie" Fredericks is a former track and field athlete from Namibia. Running in the 100 metres and 200 metres, he won four silver medals at the Olympic Games, making him Namibia's only able-bodied Olympic medalist until Christine Mboma's silver medal at the 2020 Olympics in Tokyo. He also won gold medals at the World Championships, World Indoor Championships, All-Africa Games and Commonwealth Games. He is the world indoor record-holder for 200 metres, with a time of 19.92 seconds set in 1996.