The men's 100 metres sprint event at the 2008 Olympic Games took place on 15 and 16 August at the Beijing National Stadium. Eighty athletes from 64 nations competed. Each nation was limited to 3 athletes per rules in force since the 1930 Olympic Congress. The final was won by Jamaican Usain Bolt in a world record time of 9.69 seconds. It was Jamaica's first title in the event, and first medal in the event since 1976. Jamaica became the first country to join the men's 100 metre winners since Trinidad and Tobago, also in 1976; Richard Thompson won that country's fourth overall medal in the event with his silver.

Usain St. Leo Bolt is a retired Jamaican sprinter, widely considered to be the greatest sprinter of all time. He is the world record holder in the 100 metres, 200 metres, and 4 × 100 metres relay.