Azoth is a universal remedy or potent solvent sought after in the realm of alchemy, akin to alkahest—a distinct alchemical substance. The quest for Azoth was the crux of numerous alchemical endeavors,
Fourth woodcut illustration from Basil Valentine's Azoth (1613)
In alchemy and philosophy, prima materia, materia prima, or first matter, is the ubiquitous starting material required for the alchemical magnum opus and the creation of the philosopher's stone. It is
Alchemical emblem depicting the omnipresence of the philosophical matter. "The Stone that is Mercury, is cast upon the Earth, exalted on Mountains, resides in the Air, and is nourished in the Waters." (Michael Maier's Atalanta Fugiens. 1617.) The cubes represent prima materia.