The Barrymore family, and the related Drew family, form a British-American acting dynasty which traces its acting roots to the mid-19th century London stage. After migrating to the United States, members of the family appeared in motion pictures.

Lionel Barrymore was an American actor of stage, screen and radio as well as a film director. He won an Academy Award for Best Actor for his performance in A Free Soul (1931), and is known to modern audiences for the role of villainous Mr. Potter in Frank Capra's 1946 film It's a Wonderful Life.