The Battle of Campbell's Station saw Confederate forces under Lieutenant General James Longstreet attack Union troops led by Major General Ambrose Burnside at Campbell's Station, Knox County, Tennessee, during the Knoxville Campaign of the American Civil War. Longstreet hoped to crush the Union Army of the Ohio forces before they could retreat to Knoxville. During the fighting, the Confederates forced the Union troops to fall back from five separate positions. However, the final result was that Burnside's troops conducted a successful fighting withdrawal.

Ambrose Everett Burnside was an American army officer and politician who became a senior Union general in the Civil War and three-time Governor of Rhode Island, as well as being a successful inventor and industrialist.