The Battle of Pensacola took place during the Creek War, part of the War of 1812, in which American forces fought against forces from the kingdoms of Britain and Spain who were aided by the Creek Indians and African-American slaves allied with the British. General Andrew Jackson led his infantry against British and Spanish forces controlling the city of Pensacola in Spanish Florida. Allied forces abandoned the city, and the remaining Spanish forces surrendered to Jackson.

The Creek War, was a regional conflict between opposing Native American factions, European powers, and the United States during the early 19th century. The Creek War began as a conflict within the tribes of the Muscogee, but the United States quickly became involved. British traders and Spanish colonial officials in Florida supplied the Red Sticks with weapons and equipment due to their shared interest in preventing the expansion of the United States into regions under their control.