The Bay of Pigs Invasion was a failed military landing operation on the southwestern coast of Cuba in 1961 by Cuban Democratic Revolutionary Front (DRF), consisting of Cuban exiles who opposed Fidel Castro's Cuban Revolution, clandestinely financed and directed by the U.S. government. The operation took place at the height of the Cold War, and its failure influenced relations between Cuba, the United States, and the Soviet Union.

The United States embargo against Cuba prevents US businesses, and businesses organized under US law or majority-owned by US citizens, from conducting trade with Cuban interests. It is the most enduring trade embargo in modern history. The US first imposed an embargo on the sale of arms to Cuba on March 14, 1958, during the Fulgencio Batista regime. Again on October 19, 1960, almost two years after the Cuban Revolution had led to the deposition of the Batista regime, the U.S. placed an embargo on exports to Cuba except for food and medicine after Cuba nationalized the US-owned Cuban oil refineries without compensation. On February 7, 1962, the embargo was extended to include almost all exports. The United Nations General Assembly has passed a resolution every year since 1992 demanding the end of the US economic embargo on Cuba, with the US and Israel being the only nations to consistently vote against the resolutions.