The Beehive Cluster, is an open cluster in the constellation Cancer. One of the nearest open clusters to Earth, it contains a larger population of stars than other nearby bright open clusters holding around 1,000 stars. Under dark skies, the Beehive Cluster looks like a small nebulous object to the naked eye, and has been known since ancient times. Classical astronomer Ptolemy described it as a "nebulous mass in the breast of Cancer". It was among the first objects that Galileo studied with his telescope.

An open cluster is a type of star cluster made of tens to a few thousand stars that were formed from the same giant molecular cloud and have roughly the same age. More than 1,100 open clusters have been discovered within the Milky Way galaxy, and many more are thought to exist. Each one is loosely bound by mutual gravitational attraction and becomes disrupted by close encounters with other clusters and clouds of gas as they orbit the Galactic Center. This can result in a loss of cluster members through internal close encounters and a dispersion into the main body of the galaxy. Open clusters generally survive for a few hundred million years, with the most massive ones surviving for a few billion years. In contrast, the more massive globular clusters of stars exert a stronger gravitational attraction on their members, and can survive for longer. Open clusters have been found only in spiral and irregular galaxies, in which active star formation is occurring.