Biggleswade railway station serves the market town of Biggleswade in Bedfordshire, England. It is on the East Coast Main Line, 41 miles 13 chains from London King's Cross. The station is managed by Great Northern, although most services are operated by Thameslink.

Biggleswade is a market town and civil parish in Central Bedfordshire in Bedfordshire, England. It lies on the River Ivel, 11 miles (18 km) south-east of Bedford. Its population was 16,551 in the 2011 United Kingdom census, This figure increased by 36% to 22,541 at the time of the 2021 United Kingdom census.