The Blackstone River and Canal Heritage State Park is a part of the state park system of the Commonwealth of Massachusetts, managed by the Massachusetts Department of Conservation and Recreation (DCR). This 1,000-acre (4.0 km2) park "recalls the role of canals in transporting raw materials and manufactured goods between emerging industrial centers." The Blackstone River and Canal Heritage State Park at Uxbridge, Massachusetts, is the midpoint of the Blackstone River Valley National Heritage Corridor of the National Park System. The Blackstone River and Valley is where the industrial revolution was born in America. The southern entrance to this state park is the site of the historic Stanley Woolen Mill, currently being redeveloped for commercial and tourism. The Native American Nipmuc name for the village here was "Wacentug", translated as "bend in the river".

Uxbridge is a town in Worcester County, Massachusetts, United States, first colonized in 1662 and incorporated in 1727. It was originally part of the town of Mendon, and named for the Earl of Uxbridge. The town is located 36 mi (58 km) southwest of Boston and 15 mi (24 km) south-southeast of Worcester, at the midpoint of the Blackstone Valley National Historic Park. The historical society notes that Uxbridge is the "Heart of The Blackstone Valley" and is also known as "the Cradle of the Industrial Revolution". Uxbridge was a prominent Textile center in the American Industrial Revolution. Two Quakers served as national leaders in the American anti-slavery movement. Uxbridge "weaves a tapestry of early America".