The Bowery Boys were a nativist, anti-Catholic, and anti-Irish criminal gang based in the Bowery neighborhood of Manhattan, New York City in the early-mid-19th century. In contrast with the Irish immigrant tenement of the Five Points, the Bowery was a more prosperous working-class community. Despite its reputation as one of the most notorious street gangs of New York City at the time, the majority of the Bowery Boys led law-abiding lives for the most part. The gang was made up exclusively of volunteer firemen—though some also worked as tradesmen, mechanics, and butchers —and would fight rival fire companies over who would extinguish a fire. The Bowery Boys often battled multiple outfits of the infamous Five Points, most notably the Dead Rabbits, with whom they feuded for decades. The uniform of a Bowery Boy generally consisted of a stovepipe hat in variable condition, a red shirt, and dark trousers tucked into boots—this style paying homage to their fireman roots.

The Bowery is a street and neighborhood in Lower Manhattan in New York City, United States. The street runs from Chatham Square at Park Row, Worth Street, and Mott Street in the south to Cooper Square at 4th Street in the north. The eponymous neighborhood runs roughly from the Bowery east to Allen Street and First Avenue, and from Canal Street north to Cooper Square/East Fourth Street. The neighborhood roughly overlaps with Little Australia. To the south is Chinatown, to the east are the Lower East Side and the East Village, and to the west are Little Italy and NoHo. It has historically been considered a part of the Lower East Side of Manhattan.