The Brisbane River is the longest river in South East Queensland, Australia, and flows through the city of Brisbane, before emptying into Moreton Bay on the Coral Sea. John Oxley, the first European to explore the river, named it after the Governor of New South Wales, Sir Thomas Brisbane in 1823. The penal colony of Moreton Bay later adopted the same name, eventually becoming the present city of Brisbane. The river is a tidal estuary and the water is brackish from its mouth through the majority of the Brisbane metropolitan area westward to the Mount Crosby Weir. The river is wide and navigable throughout the Brisbane metropolitan area.

John Joseph William Molesworth Oxley was an explorer and surveyor of Australia in the early period of British colonisation. He served as Surveyor General of New South Wales and is perhaps best known for his two expeditions into the interior of New South Wales and his exploration of the Tweed River and the Brisbane River in what is now the state of Queensland.