Buffalo is a town in Scott County, Iowa, United States. The population was 1,176 at the 2020 census. Buffalo is located on the Mississippi River. The town is a part of the Quad Cities Metropolitan Area.

Scott County is a county located in the U.S. state of Iowa. As of the 2020 census, the population was 174,669, making it the third-most populous county in Iowa. The county seat is Davenport.