Burlington is the most populous city in the U.S. state of Vermont and the seat of Chittenden County. It is located 45 miles (72 km) south of the Canada–United States border and 95 miles (153 km) south of Montreal. As of the 2020 U.S. census, the population was 44,743. It is the least populous city in the 50 U.S. states to be the most populous city in its state.

Vermont is a landlocked state in the New England region of the Northeastern United States. It borders Massachusetts to the south, New Hampshire to the east, New York to the west, and the Canadian province of Quebec to the north. As of the 2020 U.S. census, the state had a population of 643,503, ranking it the second least populated U.S. state ahead of Wyoming. It is the nation's sixth smallest state in area. The state's capital of Montpelier is the least populous U.S. state capital. No other U.S. state has a most populous city with fewer residents than Burlington. Vermont is also well known for being the largest producer of true maple syrup in the United States for over 200 years.