The C-Group culture is an archaeological culture found in Lower Nubia, which dates from c. 2400 BCE to c. 1550 BCE. It was named by George A. Reisner. With no central site and no written evidence about what these people called themselves, Reisner assigned the culture a letter. The C-Group arose after Reisner's A-Group and B-Group cultures, and around the time the Old Kingdom was ending in Ancient Egypt.

Nubia is a region along the Nile river encompassing the area between the first cataract of the Nile and the confluence of the Blue and White Niles, or more strictly, Al Dabbah. It was the seat of one of the earliest civilizations of ancient Africa, the Kerma culture, which lasted from around 2500 BC until its conquest by the New Kingdom of Egypt under Pharaoh Thutmose I around 1500 BC, whose heirs ruled most of Nubia for the next 400 years. Nubia was home to several empires, most prominently the Kingdom of Kush, which conquered Egypt in the eighth century BC during the reign of Piye and ruled the country as its 25th Dynasty.