The COVID-19 pandemic in Rwanda was a part of the ongoing worldwide pandemic of coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2. The virus was confirmed to have reached Rwanda in March 2020. Rwanda's response to the pandemic has received international praise for its effectiveness. Despite limited resources, the country's well organised healthcare system, rapid deployment of testing procedures and high public trust in medical authorities have led to a successful public health response. As of 15 December 2021, there were 100,763 total confirmed cases, 1,344 confirmed deaths, 7 million first vaccine shots, and 1 critical case.

COVID-19 testing involves analyzing samples to assess the current or past presence of SARS-CoV-2. The two main types of tests detect either the presence of the virus or antibodies produced in response to infection. Molecular tests for viral presence through its molecular components are used to diagnose individual cases and to allow public health authorities to trace and contain outbreaks. Antibody tests instead show whether someone once had the disease. They are less useful for diagnosing current infections because antibodies may not develop for weeks after infection. It is used to assess disease prevalence, which aids the estimation of the infection fatality rate.