The Cadillac V-12 is an exclusive V-12 powered luxury car that was manufactured by Cadillac from the 1930 through the 1937. Below only the maker's top-of-the-line Cadillac V-16 line, these were powered by the Cadillac V12 engine, furnished with similar custom bodies, and built in relatively small numbers. A total of 10,903 were made in the seven model years that the automobile was built, with the majority having been constructed in its inaugural year. It was Cadillac's first, and is to date, Cadillac's only standard production V-12 automobile.

A V12 engine is a twelve-cylinder piston engine where two banks of six cylinders are arranged in a V configuration around a common crankshaft. V12 engines are more common than V10 engines. However, they are less common than V8 engines.