James Calvin "Cal" Cunningham III is an American lawyer, politician, and retired military officer. A member of the Democratic Party and a lieutenant colonel in the United States Army Reserve, he served one term as a North Carolina state senator from 2001 to 2003. Having previously run for United States Senate in a 2010 primary, Cunningham was the Democratic nominee for the 2020 U.S. Senate election in North Carolina, narrowly losing to incumbent Republican Thom Tillis.

The 2010 United States Senate election in North Carolina was held on November 2, 2010. The filing deadline for the primaries was February 26; the primaries were held on May 4, with a Democratic primary runoff held on June 22. Incumbent Republican U.S. Senator Richard Burr won re-election to a second term. Burr is the first incumbent to win re-election for this seat since Sam Ervin's last re-election in 1968.