Calhoun County is a county in the east central part of the U.S. state of Alabama. As of the 2020 census, the population was 116,441. Its county seat is Anniston. It is named in honor of John C. Calhoun, a US Senator from South Carolina.

The 2020 United States presidential election in Alabama took place on Tuesday, November 3, 2020, as part of the 2020 United States presidential election in which all 50 states and the District of Columbia participated. Alabama voters chose nine electors to represent them in the Electoral College via a popular vote pitting incumbent Republican President Donald Trump and his running mate, incumbent Vice President Mike Pence, against Democratic challenger and former Vice President Joe Biden and his running mate, United States Senator Kamala Harris of California. Also on the ballot was the Libertarian nominee, psychology lecturer Jo Jorgensen and her running mate, entrepreneur and podcaster Spike Cohen. Write-in candidates were permitted without registration, and their results were not individually counted.