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Multiple mutations in cancer cells
Multiple mutations in cancer cells
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Some acetylations and some methylations of lysines (symbol K) are activation signals for transcription when present on a nucleosome, as shown in the t
Some acetylations and some methylations of lysines (symbol K) are activation signals for transcription when present on a nucleosome, as shown in the top figure. Some methylations on lysines or arginine (R) are repression signals for transcription when present on a nucleosome, as shown in the bottom figure. Nucleosomes consist of four pairs of histone proteins in a tightly assembled core region plus up to 30% of each histone remaining in a loosely organized tail
including medial prefrontal cortex (mPFC)
including medial prefrontal cortex (mPFC)
Cytosine and 5-methylcytosine
Cytosine and 5-methylcytosine
Image: Histone tails set for transcriptional repression
Image: Histone tails set for transcriptional repression