The Carnegie Institution for Science, also known as Carnegie Science and the Carnegie Institution of Washington, is an organization in the United States established to fund and perform scientific research. The institution is headquartered in Washington, D.C. As of June 30, 2020, the Institution's endowment was valued at $926.9 million. In 2018 the expenses for scientific programs and administration were $96.6 million. Eric Isaacs is president of the institution.

Andrew Carnegie was a Scottish-American industrialist and philanthropist. Carnegie led the expansion of the American steel industry in the late 19th century and became one of the richest Americans in history. He became a leading philanthropist in the United States, Great Britain, and the British Empire. During the last 18 years of his life, he gave away around $350 million, almost 90 percent of his fortune, to charities, foundations and universities. His 1889 article proclaiming "The Gospel of Wealth" called on the rich to use their wealth to improve society, expressed support for progressive taxation and an estate tax, and stimulated a wave of philanthropy.