The Caroní River is the second most important river of Venezuela, the second in flow, and one of the longest, 952 kilometres (592 mi) from the Kukenan tepui through to its confluence with the Orinoco River. The name "Caroní" is applied starting from the confluence of the Kukenan with the Yuruaní River at 182 kilometres (113 mi) from the source of the Kukenan and 770 kilometres (480 mi) from its discharge in the Orinoco. The confluence takes place in Bolivar State. The Caroní River is the longest river located entirely within Venezuela.

The Orinoco is one of the longest rivers in South America at 2,250 kilometres (1,400 mi).