Casino Lisboa is a casino located at Parque das Nações in the city of Lisbon, Portugal. It was inaugurated and opened to the public on April 19, 2006.

The Parque das Nações, colloquially known as Expo, is a freguesia and typical quarter of Lisbon, the capital city of Portugal. Located in eastern Lisbon, Parque das Nações is to the east of Olivais, northeast of Marvila, and directly south of Lisbon's border with Loures. The population in 2021 was 22,382.