Cass City is a village in Elkland Township, Tuscola County in the Flint/Tri-Cities area of the U.S. state of Michigan. The population was 2,428 at the 2010 U.S. Census and 2,643 at the 2000 U.S. Census. It is located along M-81 approximately four miles (6.4 km) west of that highway's intersection with M-53. Cass City is surrounded by several communities including Colwood, Deford, Elmwood and Ellington.

M-53 is a north–south state trunkline highway in the US state of Michigan that connects Detroit to The Thumb region. The highway starts in Detroit at a connection with M-3 and ends in Port Austin, Michigan at M-25. In between, the trunkline passes through the northern suburbs of Metro Detroit, connects to freeways like Interstate 69 (I-69) and provides access to rural farmland. In Macomb County, M-53 follows the Christopher Columbus Freeway and POW/MIA Memorial Freeway, while the remainder of the highway is known as Van Dyke Avenue in the metro area or Van Dyke Road elsewhere. The highway has also been named the Earle Memorial Highway for one of the pioneers of the Good Roads Movement and Michigan's highway system.