Castelmezzano is a town and comune in the province of Potenza, in the Southern Italian region of Basilicata. It is bounded by the comuni of Albano di Lucania, Anzi, Laurenzana, Pietrapertosa, Trivigno.

I Borghi più belli d'Italia is a non-profit private association of small Italian towns of strong historical and artistic interest, that was founded in March 2001 on the initiative of the Tourism Council of the National Association of Italian Municipalities, with the aim of preserving and maintaining villages of quality heritage. Its motto is Il fascino dell'Italia nascosta.