Cereulide is a heat-stable toxin produced by some strains of Bacillus cereus, B. megaterium and related species. It is a potent cytotoxin that causes nausea and vomiting.
The following depicts the non-ribosomal peptide synthetase of the cereulide tetrapeptide. The growing and modified peptide can be seen on each Thiolation (T) domain. The new part of the molecule being inserted between the sulphur atom and the first carbonyl groep.
Bacillus cereus is a Gram-positive rod-shaped bacterium commonly found in soil, food, and marine sponges. The specific name, cereus, meaning "waxy" in Latin, refers to the appearance of colonies grown
Cereulide
…Cereulide is a heat-stable toxin produced by some strains of Bacillus cereus, B. megaterium and related species. It is a potent cytotoxin that causes nausea and vomiting. Cereulide acts as an ionophore with a high affinity for…
Electron micrograph of Bacillus cereus
Bacillus cereus endospore stain
Bacillus cereus colonies on the indicator media Brilliance Bacillus cereus agar