The Chūō Main Line , commonly called the Chūō Line, is one of the major trunk railway lines in Japan. It connects Tokyo and Nagoya, although it is the slowest direct railway connection between the two cities; the coastal Tōkaidō Main Line is slightly faster, and the Tōkaidō Shinkansen is currently the fastest rail link between the cities.

Nagoya is the largest city in the Chūbu region, the fourth-most populous city proper with a population of 2.3 million in 2020, and the principal city of the Chūkyō metropolitan area, which is the third-most populous metropolitan area in Japan with a population of 10.11 million. Located on the Pacific coast in central Honshu, it is the capital and most populous city of Aichi Prefecture, with the Port of Nagoya being Japan's largest seaport.