The Charleston metropolitan area is an urban area centered around Charleston, South Carolina. The U.S. Office of Management and Budget designates the area as the Charleston-North Charleston, SC Metropolitan Statistical Area, a metropolitan statistical area used for statistical purposes only by the United States Census Bureau and other federal agencies. The OMB defines the area as comprising Berkeley, Charleston and Dorchester counties, an area with 799,636 residents in the 2020 census. Principal cities include Charleston, North Charleston, and Summerville. The area is commonly referred to as the Tri-County Area or the Lowcountry, though the latter term has historically referred to South Carolina's southern coast in general.

Charleston is the most populous city in the U.S. state of South Carolina, the county seat of Charleston County, and the principal city in the Charleston metropolitan area. The city lies just south of the geographical midpoint of South Carolina's coastline on Charleston Harbor, an inlet of the Atlantic Ocean formed by the confluence of the Ashley, Cooper, and Wando rivers. Charleston had a population of 150,227 at the 2020 census. The population of the Charleston metropolitan area, comprising Berkeley, Charleston, and Dorchester counties, was estimated to be 849,417 in 2023. It ranks as the third-most populous metropolitan statistical area in the state, and the 71st-most populous in the United States.