The chief of staff of the Air Force is the service chief of the United States Air Force. They are the principal military advisor to the secretary of the Air Force on matter pertaining to the Air Force. They are a member of the Joint Chiefs of Staff, and thereby a military adviser to the National Security Council, the secretary of defense, and the President. The chief of staff is typically the highest-ranking officer on active duty in the Air Force, unless the chairman and/or the vice chairman of the Joint Chiefs of Staff are Air Force officers.

The United States Air Force (USAF) is the air service branch of the United States Armed Forces, and is one of the eight uniformed services of the United States. Originally created on 1 August 1907, as a part of the United States Army Signal Corps, the USAF was established as a separate branch of the United States Armed Forces in 1947 with the enactment of the National Security Act of 1947. It is the second youngest branch of the United States Armed Forces and the fourth in order of precedence. The United States Air Force articulates its core missions as air supremacy, global integrated intelligence, surveillance and reconnaissance, rapid global mobility, global strike, and command and control.