The Chiltern-Mt Pilot National Park is a national park that is located in the Hume region of Victoria, Australia. The 21,650-hectare (53,500-acre) national park is situated approximately 275 kilometres (171 mi) northeast of Melbourne, and extends west from Beechworth across the Hume Freeway and the Albury-Melbourne railway line to the west of Chiltern.

The Hume is an economic rural region located in the north-eastern part of Victoria, Australia. Comprising an area in excess of 40,000 square kilometres (15,000 sq mi) with a population that has grown from 263,000 to 309,684, the Hume region includes the local government areas of Alpine Shire, Rural City of Benalla, City of Wodonga, City of Greater Shepparton, Shire of Indigo, Shire of Mansfield, Shire of Strathbogie, Shire of Towong and the Rural City of Wangaratta, and also includes five unincorporated areas encompassing the alpine ski resorts in the region.