The Chiquitano or Chiquitos are an indigenous people of Bolivia, with a small number also living in Brazil. The Chiquitano primarily live in the Chiquitania tropical savanna of Santa Cruz Department, Bolivia, with a small number also living in Beni Department and in Mato Grosso, Brazil. In the 2012 census, self-identified Chiquitanos made up 1.45% of the total Bolivian population or 145,653 people, the largest number of any lowland ethnic group. A relatively small proportion of Bolivian Chiquitanos speak the Chiquitano language. Many reported to the census that they neither speak the language nor learned it as children. The Chiquitano ethnicity emerged among socially and linguistically diverse populations required to speak a common language by the Jesuit Missions of Chiquitos.

Santa Cruz is the largest of the nine constituent departments of Bolivia, occupying about one-third (33.74%) of the country's territory. With an area of 370,621 km2 (143,098 sq mi), it is slightly smaller than Japan or the US state of Montana. It is located in the eastern part of the country, sharing borders in the north and east with Brazil and with Paraguay in the south.