Chloral hydrate is a geminal diol with the formula Cl3C−CH(OH)2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer and more effective alternatives but it remained in usage in the United States until at least the 1970s. It sometimes finds usage as a laboratory chemical reagent and precursor. It is derived from chloral (trichloroacetaldehyde) by the addition of one equivalent of water.

Gabriel Charles Dante Rossetti, generally known as Dante Gabriel Rossetti, was an English poet, illustrator, painter, translator, and member of the Rossetti family. He founded the Pre-Raphaelite Brotherhood in 1848 with William Holman Hunt and John Everett Millais. Rossetti inspired the next generation of artists and writers, William Morris and Edward Burne-Jones in particular. His work also influenced the European Symbolists and was a major precursor of the Aesthetic movement.