Christianity is the largest religion in Mizoram. The majority 87% of Mizoram population are Christian in various denominations, predominantly Presbyterian. More than 98% of the Mizos are Christians by faith. The Government of Mizoram declared that Christianity plays a very important role among the daily life of Mizo community and therefore further declared that Christianity as the religion of the state. The culture of Mizoram is mainly influenced by Christianity. Hence, Christianity was given a special status on the state by the government while maintaining a minimum level of secular environment and approach. In June 2018, the government of Mizoram including Vanlalruata, president of anti-corruption organisation-turned-political party, People's Representation for Identity and Status of Mizoram claim that Mizoram is a Christian state. Hindus form a small minority (3.55%) mainly of Manipuris and there are also around (7.93%) Buddhists according to the 2001 census, mostly made up from Chakma settlers of Arakan origin. There are about 8,000 mostly ethnic Mizo followers of a Judaic group Bnei Menashe, who claim descent from the biblical Menasseh. Muslims make up about 1.1% of the state population.

Mizoram Presbyterian Church Synod is the largest Christian denomination in Mizoram, northeast India. It was a direct progeny of the Calvinistic Methodist Church in Wales. It was the first church in Mizoram and is now one of the constituent bodies of a larger denomination Presbyterian Church of India (PCI), which has its headquarters in Shillong, Meghalaya. The administrative body called the Mizoram Synod has its headquarters at Mission Veng, Aizawl. As the first church, it remains the largest denomination in Mizoram.