Clyde is a village in Wayne County, New York, United States. The population was 2,093 at the 2010 census. It was named after the River Clyde, in Scotland, and the village sits on the Clyde River, a tributary of the Seneca River.

The Clyde River is a main tributary which feeds the Seneca River in Seneca County, New York, United States. It begins at the hamlet of Lyons in nearby Wayne County and meanders for approximately 27 miles from west to east before emptying into the Seneca River in the town of Tyre at Montezuma National Wildlife Refuge. Much of the original river has been channeled through to form part of the Erie Canal. A number of tributaries feed the Clyde River along its route.