Computer case screws are the hardware used to secure parts of a PC to the case. Although there are numerous manufacturers of computer cases, they have generally used three thread sizes. The Unified Thread Standard (UTS) originates from the United States, while the ISO metric screw thread is standardized worldwide. In turn, these thread standards define preferred size combinations that are based on generic units—some on the inch and others on the millimetre.

A computer case, also known as a computer chassis, is the enclosure that contains most of the hardware of a personal computer. The components housed inside the case are referred as the internal hardware, while hardware outside the case are known as peripherals.