Constantine I, also known as Constantine the Great, was a Roman emperor from AD 306 to 337 and the first Roman emperor to convert to Christianity. He played a pivotal role in elevating the status of Christianity in Rome, decriminalizing Christian practice and ceasing Christian persecution in a period referred to as the Constantinian shift. This initiated the cessation of the established ancient Roman religion. Constantine is also the originator of the religiopolitical ideology known as Constantinism, which epitomizes the unity of church and state, as opposed to separation of church and state. He founded the city of Constantinople and made it the capital of the Empire, which remained so for over a millenium.

The fall of the Western Roman Empire, also called the fall of the Roman Empire or the fall of Rome, was the loss of central political control in the Western Roman Empire, a process in which the Empire failed to enforce its rule, and its vast territory was divided between several successor polities. The Roman Empire lost the strengths that had allowed it to exercise effective control over its Western provinces; modern historians posit factors including the effectiveness and numbers of the army, the health and numbers of the Roman population, the strength of the economy, the competence of the emperors, the internal struggles for power, the religious changes of the period, and the efficiency of the civil administration. Increasing pressure from invading barbarians outside Roman culture also contributed greatly to the collapse. Climatic changes and both endemic and epidemic disease drove many of these immediate factors. The reasons for the collapse are major subjects of the historiography of the ancient world and they inform much modern discourse on state failure.