The Częstochowa Ghetto was a World War II ghetto set up by Nazi Germany for the purpose of persecution and exploitation of local Jews in the city of Częstochowa during the German occupation of Poland. The approximate number of people confined to the ghetto was around 40,000 at the beginning and in late 1942 at its peak, immediately before mass deportations, 48,000. Most ghetto inmates were delivered by the Holocaust trains to Treblinka extermination camp, where they were murdered. In June 1943, the remaining ghetto inhabitants launched the Częstochowa Ghetto uprising, which was extinguished by the SS after a few days of fighting.

Częstochowa is a city in southern Poland on the Warta River with 214,342 inhabitants, making it the thirteenth-largest city in Poland. It is situated in the Silesian Voivodeship. However, Częstochowa is historically part of the Lesser Poland region, not of Silesia, and before 1795, it belonged to the Kraków Voivodeship. Częstochowa is located in the Kraków-Częstochowa Upland. It is the largest economic, cultural and administrative hub in the northern part of the Silesian Voivodeship.