Darius I, commonly known as Darius the Great, was a Persian ruler who served as the third King of Kings of the Achaemenid Empire, reigning from 522 BCE until his death in 486 BCE. He ruled the empire at its territorial peak, when it included much of Western Asia, parts of the Balkans and the Caucasus, most of the Black Sea's coastal regions, Central Asia, the Indus Valley in the far east, and portions of North Africa and Northeast Africa including Egypt (Mudrâya), eastern Libya, and coastal Sudan.

Achaemenid Macedonia refers to the period in which the ancient Greek Kingdom of Macedonia was under the sway of the Achaemenid Persians. In 512/511 BC, the Persian general Megabyzus forced the Macedonian king Amyntas I to make his kingdom a vassal of the Achaemenids. In 492 BC, following the Ionian Revolt, the Persian general Mardonius firmly re-tightened the Persian grip in the Balkans, making Macedon a fully subordinate kingdom within the Achaemenid domains and part of its administrative system. Macedonia served the Achaemenid Empire during the Greco-Persian Wars in their invasion of mainland Greece. They regained independence following the defeat and withdrawal of the Achaemenid Empire in 479 BC.