The DeSoto Airflow is a full-sized automobile built by DeSoto during model years 1934, 1935 and 1936. DeSoto received the then-revolutionary Airflow model due to its price structure relationship to larger and more expensive Chrysler brand cars. The 1934 Airflow models are noted for their unique styling. They generate interest for their engineering innovations. It has a 115.5 in (2,934 mm) wheelbase.

DeSoto was an American automobile marque that was manufactured and marketed by the DeSoto division of Chrysler Corporation from 1928 to the 1961 model year. More than two million passenger cars and trucks bore the DeSoto brand in North American markets during its existence.