Dead Letter Office is a rarities and B-sides collection by R.E.M., released in April 1987. The album is essentially a collection of many additional recordings R.E.M. made from before Murmur to Lifes Rich Pageant that were outtakes or released as B-sides to their singles internationally. Many of the tracks are favorite cover versions indicating the band's disparate influences and musical tastes, including three Velvet Underground covers, and songs by Aerosmith, Roger Miller, and fellow Athenians Pylon ("Crazy").

R.E.M. was an American alternative rock band from Athens, Georgia, formed in 1980 by drummer Bill Berry, guitarist Peter Buck, bassist Mike Mills, and lead vocalist Michael Stipe, who were students at the University of Georgia. One of the first alternative rock bands, R.E.M. was noted for Buck's ringing, arpeggiated guitar style; Stipe's distinctive vocal quality, unique stage presence, and obscure lyrics; Mills's melodic bass lines and backing vocals; and Berry's tight, economical drumming style. In the early 1990s, other alternative rock acts such as Nirvana and Pavement viewed R.E.M. as a pioneer of the genre. After Berry left the band in 1997, the band continued its career in the 2000s with mixed critical and commercial success. The band broke up amicably in 2011 with members devoting time to solo projects after having sold more than 90 million albums worldwide and becoming one of the world's best-selling music acts.