R.E.M. was an American alternative rock band from Athens, Georgia, formed in 1980 by drummer Bill Berry, guitarist Peter Buck, bassist Mike Mills, and lead vocalist Michael Stipe, who were students at the University of Georgia. One of the first alternative rock bands, R.E.M. was noted for Buck's ringing, arpeggiated guitar style; Stipe's distinctive vocal quality, unique stage presence, and obscure lyrics; Mills's melodic bass lines and backing vocals; and Berry's tight, economical drumming style. In the early 1990s, other alternative rock acts such as Nirvana and Pavement viewed R.E.M. as a pioneer of the genre. After Berry left the band in 1997, the band continued its career in the 2000s with mixed critical and commercial success. The band broke up amicably in 2011 with members devoting time to solo projects after having sold more than 90 million albums worldwide and becoming one of the world's best-selling music acts.

Alternative rock is a category of rock music that evolved from the independent music underground of the 1970s. Alternative rock acts achieved mainstream success in the 1990s with the likes of the grunge, shoegaze, and Britpop subgenres in the United States and United Kingdom, respectively. During this period, many record labels were looking for "alternatives", as many corporate rock, hard rock, and glam metal acts from the 1980s were beginning to grow stale throughout the music industry. The emergence of Generation X as a cultural force in the 1990s also contributed greatly to the rise of alternative rock.