Dedication 2 is the sixth mixtape by Lil Wayne, hosted by DJ Drama. It is a sequel to Lil Wayne's previous mixtape, The Dedication, and is second in DJ Drama's Gangsta Grillz series with Lil Wayne. It is one of the few mixtapes in the hip hop genre to be both financially successful and critically acclaimed. Despite its illegal use of unlicensed instrumentals and samples, it was sold through iTunes and retail stores such as Best Buy and FYE, was widely reviewed in the mainstream media, and peaked at #69 on Billboard's "Top R&B/Hip-Hop Albums” chart. The cover shows Lil Wayne with "Fear God" tattooed on his eyelids. Much of the mixtape showcases Lil Wayne's free associating rhymes and "liquid non-sequiturs."

Dwayne Michael Carter Jr., known professionally as Lil Wayne, is an American rapper, singer, songwriter, and record executive. He is regarded as one of the most influential hip hop artists of his generation, and is often mentioned among the greatest rappers of all time. He was signed by American rapper Birdman to his record label Cash Money Records in 1995, becoming the youngest member of the label at age eleven. In the following years, he emerged as the flagship artist of Cash Money Records before ending his association with the imprint in June 2018.