Delaware Route 141 (DE 141) is a state highway that serves as a western bypass of Wilmington, Delaware. Its southern terminus is at DE 9 and DE 273 in New Castle and its northern terminus is an interchange with U.S. Route 202 (US 202) and DE 261 near Fairfax. The route heads north from DE 9 and DE 273 on four-lane divided Basin Road, becoming concurrent with US 202 at an interchange with US 13/US 40 in Wilmington Manor, and passes to the east of Wilmington Airport. The highway becomes a freeway and reaches an interchange with Interstate 95 (I-95) and I-295, at which point US 202 splits from DE 141. The DE 141 freeway continues north through Newport to Prices Corner. Here, the freeway segment ends and DE 141 continues northeast as a surface road, with another brief freeway segment in Greenville. The route heads east across the Brandywine Creek on the Tyler-McConnell Bridge and continues to US 202 and DE 261.

New Castle County is the northernmost of the three counties of the U.S. state of Delaware. As of the 2020 census, the population was 570,719, making it the most populous county in Delaware, with nearly 60% of the state's population of 989,948. The county seat is Wilmington, which is also the state's most populous city.