In biology, depolarization or hypopolarization is a change within a cell, during which the cell undergoes a shift in electric charge distribution, resulting in less negative charge inside the cell com
Action potential in a neuron, showing depolarization, in which the cell's internal charge becomes less negative (more positive), and repolarization, where the internal charge returns to a more negative value.
Voltage-gated sodium channel. Open channel (top) carries an influx of Na+ ions, giving rise to depolarization. As the channel becomes closed/inactivated (bottom), the depolarization ends.